Arizona Health Sciences

Douglas F. Larson, Ph.D.

Professor Emeritus, Department of Surgery

Contact Information

Office: 6152
Phone: (520) 626-6494
Email: dflarson@email.arizona.edu

Education:

University of Arizona, 1984 (Ph.D.)

Honors & Awards:

Louis J. Kettel Faculty Mentor Award, Clinical Sciences Mentor, Medical Student Research Program, 1996
Vernon and Virginia Furrow Award, Excellence in Graduate
Student Education, 2009

Major Areas of Research Interest:

Immunological role of the endothelium
Heart and lung transplantation

Sponsored Research Through MSRP:

David Rigberg (MSRP 1991): "Temporal relationship of MHC expression to the time of rejection in lung allografts."
Pei Hsuan Tsau (MSRP 1991): "Expression of MHC-II as a marker of rejection in rats."

Robert Berger (MSRP 1992): "Orthotopic transplantation of the pig heart after 24 hours storage in the Arizona heart preservation system."

Susan Bond (MSRP 1993): "Cyclosporin A as a cardioplegia in transplanted rabbit hearts."

Wendi Carns (MSRP 1996): "Effects of immunotherapy on MDR1 efflux function."

Michael Levin (MSRP 1996): "A comparison of multidrug resistance protein expression in peripheral lymphocytes to heart allograft infiltrated lymphocytes."

James Ridgeway (MSRP 2000): "Comparison of RATG to thymogobulin in the human transplant patient."
Jyoti Bollmann (MSRP 2001): "Phospholamban expression and function in heart failure."
Tara Kelley (MSRP 2001): "SERCA2a function and expression in heart failure."

Kathyrn Bradley (MSRP 2005): "T-Lymphocytes of the immune system play a role in cardiac remodeling contributing to diastolic heart failure."

José Anaya (MSRP 2006): "Immunomodulation: Cardiovascular structure and function."

Vanessa Tang (MSRP 2009): "The role of toll-like receptor-9 (TLR-9) in the pathogenesis of primary hypertension."

Pablo Sanchez (MSRP 2011): "Qualification of Th 17 and Treg Lymphocyte-mediated Pathway of Hypertension on Extracellular Remodeling of Collagen-elastin Cross-linking Through Lysyl Oxidase Ensyme"

NIH Undergraduate Diversity Program:

Odelia Francisco, 2011

Advanced Research - Research Distinction Track (RDT):

José Anaya (Class of 2009): "Immunomodulation: Cardiovascular structure and function."

NIH High School Student Research Program:

Mariel Velez, Salpointe Catholic High School, 1993

Amber Tiffany (Peart-) Dickerson, Chaparral High School (Scottsdale), 1994

Jorge Salazar, Pueblo High School, 1995

Kay Yeung, Sahuaro High School, 1995

Jorge Alberto Salazar, Pueblo High School, 1995 and 1996

Lucinda Cabrera Cubillas, Yuma High School, 1997

Viviana M. Hurtado, Pueblo High School, 1999

Joseph Charles Johnston, Canyon del Oro High School, 2000

David Dino Necoechea, Rincon High School, 2004

Reymundo Galvez, Nogales High School, 2005

Gildardo F. Galaviz, San Luis High School, 2008

Okongo Majok, Catalina Magnet High School, 2009

Odelia Francisco, Baboquivari High School, 2011

Angela Johnson, Baboquivari High School, 2011

Devin A. Noriega, Pima Partnership High School,2012

NIH K-12 Science Teacher Program:

Valerie S. Yellen, Yuma High School, 2000

Research Interests: 

Immunopharmacology: pharmacology and design of selective immunosuppressive therapies for solid organ transplantation and auto-immune diseases.