Arizona Health Sciences

Publications

Year of Publication Title Faculty Association
2017 Blocking CRMP2 SUMOylation reverses neuropathic pain. Rajesh Khanna
2017 Genetic and pharmacological antagonism of NK1 receptor prevents opiate abuse potential. Rajesh Khanna
2017 Targeting a Potassium Channel/Syntaxin Interaction Ameliorates Cell Death in Ischemic Stroke. Rajesh Khanna
2017 A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function. Rajesh Khanna
2017 Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides. Rajesh Khanna
2017 Long-lasting antinociceptive effects of green light in acute and chronic pain in rats. Rajesh Khanna
2016 Sensitization of Ion Channels Contributes to Central and Peripheral Dysfunction in Neurofibromatosis Type 1. Rajesh Khanna
2016 (S)-Lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology. Rajesh Khanna, May Khanna, Ph.D., Amol Patwardhan, M.D., Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD, Yanhua Xie, Ph.D.
2015 CRMP5 Controls Glioblastoma Cell Proliferation and Survival through Notch-Dependent Signaling. Rajesh Khanna
2015 Collapsin response mediator protein 3 increases the dendritic arborization of hippocampal neurons. Rajesh Khanna
2015 Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis. Todd Vanderah, PhD
2015 Chimeric derivatives of functionalized amino acids and α-aminoamides: compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels. Rajesh Khanna
2015 A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors. Rajesh Khanna, May Khanna, Ph.D., Tally Largent-Milnes, Ph.D., Todd Vanderah, PhD
2015 Therapeutic potential of peroxynitrite decomposition catalysts: a patent review. Todd Vanderah, PhD
2015 Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states. Frank Porreca, PhD, Todd Vanderah, PhD
2015 Orthopedic surgery and bone fracture pain are both significantly attenuated by sustained blockade of nerve growth factor. Patrick W Mantyh, Ph.D.
2015 (S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5. Rajesh Khanna, May Khanna, Ph.D.
2015 Spinal dopaminergic projections control the transition to pathological pain plasticity via a D1/D5-mediated mechanism. Patrick W Mantyh, Ph.D.
2014 Animal models for opioid addiction drug discovery. Tally Largent-Milnes, Ph.D., Todd Vanderah, PhD
2014 Discovery of amphipathic dynorphin A analogues to inhibit the neuroexcitatory effects of dynorphin A through bradykinin receptors in the spinal cord. Victor Hruby, Ph.D., Josephine Lai , Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD, Yanhua Xie, Ph.D.
2014 Differential regulation of collapsin response mediator protein 2 (CRMP2) phosphorylation by GSK3ß and CDK5 following traumatic brain injury. Rajesh Khanna
2014 The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth. Rajesh Khanna, May Khanna, Ph.D.
2014 Differential neuroprotective potential of CRMP2 peptide aptamers conjugated to cationic, hydrophobic, and amphipathic cell penetrating peptides. Rajesh Khanna, May Khanna, Ph.D.
2013 Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities. Victor Hruby, Ph.D., Josephine Lai , Ph.D., Tally Largent-Milnes, Ph.D., Edita Navratilova, Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD
2013 Building a better analgesic: multifunctional compounds that address injury-induced pathology to enhance analgesic efficacy while eliminating unwanted side effects. Victor Hruby, Ph.D., Tally Largent-Milnes, Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD

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