Arizona Health Sciences

Publications

Year of Publication Title Faculty Association
2015 (S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5. Rajesh Khanna, May Khanna, Ph.D.
2015 Spinal dopaminergic projections control the transition to pathological pain plasticity via a D1/D5-mediated mechanism. Patrick W Mantyh, Ph.D.
2014 Animal models for opioid addiction drug discovery. Tally Largent-Milnes, Ph.D., Todd Vanderah, PhD
2014 Discovery of amphipathic dynorphin A analogues to inhibit the neuroexcitatory effects of dynorphin A through bradykinin receptors in the spinal cord. Victor Hruby, Ph.D., Josephine Lai , Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD, Yanhua Xie, Ph.D.
2014 Clozapine acts as an agonist at serotonin 2A receptors to counter MK-801-induced behaviors through a βarrestin2-independent activation of Akt. John M. Streicher, Ph.D.
2014 Behavioral and cellular pharmacology characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan (NAQ) as a mu opioid receptor selective ligand. John M. Streicher, Ph.D.
2014 Differential neuroprotective potential of CRMP2 peptide aptamers conjugated to cationic, hydrophobic, and amphipathic cell penetrating peptides. Rajesh Khanna, May Khanna, Ph.D.
2014 Differential regulation of collapsin response mediator protein 2 (CRMP2) phosphorylation by GSK3ß and CDK5 following traumatic brain injury. Rajesh Khanna
2014 The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth. Rajesh Khanna, May Khanna, Ph.D.
2013 Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities. Victor Hruby, Ph.D., Josephine Lai , Ph.D., Tally Largent-Milnes, Ph.D., Edita Navratilova, Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD
2013 Building a better analgesic: multifunctional compounds that address injury-induced pathology to enhance analgesic efficacy while eliminating unwanted side effects. Victor Hruby, Ph.D., Tally Largent-Milnes, Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD
2013 Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism. Thomas P Davis, PhD, Patrick T Ronaldson, PhD, Todd Vanderah, PhD
2013 Effect of anchoring 4-anilidopiperidines to opioid peptides. Victor Hruby, Ph.D., Josephine Lai , Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD
2013 Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists. Patrick W Mantyh, Ph.D., Tally Largent-Milnes, Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD
2013 Development of functionally selective, small molecule agonists at kappa opioid receptors. John M. Streicher, Ph.D.
2013 Novel fentanyl-based dual μ/δ-opioid agonists for the treatment of acute and chronic pain. Victor Hruby, Ph.D., Todd Vanderah, PhD
2013 Cancer-induced bone pain: Mechanisms and models. Todd Vanderah, PhD
2013 Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at κ-opioid receptors in striatal neurons. John M. Streicher, Ph.D.
2012 Activation of TRPA1 on dural afferents: a potential mechanism of headache pain. Frank Porreca, PhD, Todd Vanderah, PhD
2012 Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy. John M. Streicher, Ph.D.
2012 Repeated morphine treatment-mediated hyperalgesia, allodynia and spinal glial activation are blocked by co-administration of a selective cannabinoid receptor type-2 agonist. Tally Largent-Milnes, Ph.D., William R. Roeske, MD, Todd Vanderah, PhD, Eva Varga, Ph.D.
2012 Tachykinin NK₁ receptor antagonist co-administration attenuates opioid withdrawal-mediated spinal microglia and astrocyte activation. Victor Hruby, Ph.D., Tally Largent-Milnes, Ph.D., Todd Vanderah, PhD, Eva Varga, Ph.D.
2012 Structure-activity relationships of trimethoxybenzyl piperazine N-type calcium channel inhibitors. Frank Porreca, PhD, Todd Vanderah, PhD
2012 Mechanisms of Bv8-induced biphasic hyperalgesia: increased excitatory transmitter release and expression. Michael H. Ossipov, Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD
2012 Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues. John M. Streicher, Ph.D.

Pages