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2010 |
A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. |
Tally Largent-Milnes, PhD, Patrick W Mantyh, Todd Vanderah, PhD |
|
2011 |
Neuroregenerative mechanisms of allopregnanolone in Alzheimer's disease. |
Roberta Diaz Brinton, Ph.D |
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2011 |
Synthesis and biological evaluation of new opioid agonist and neurokinin-1 antagonist bivalent ligands. |
Peg Davis, Victor Hruby, Ph.D., Josephine Lai , Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD, Eva Varga, Ph.D. |
|
2011 |
2-Deoxy-D-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease. |
Roberta Diaz Brinton, Ph.D |
|
2011 |
Membrane estrogen receptors mediate calcium signaling and MAP kinase activation in individual hippocampal neurons. |
Roberta Diaz Brinton, Ph.D |
|
2011 |
Inhibition of p38-MAPK signaling pathway attenuates breast cancer induced bone pain and disease progression in a murine model of cancer-induced bone pain. |
Frank Porreca, PhD, Todd Vanderah, PhD |
|
2011 |
Estrogen receptor β-selective phytoestrogenic formulation prevents physical and neurological changes in a preclinical model of human menopause. |
Roberta Diaz Brinton, Ph.D |
|
2011 |
Hippocampal responsiveness to 17β-estradiol and equol after long-term ovariectomy: implication for a therapeutic window of opportunity. |
Roberta Diaz Brinton, Ph.D |
|
2011 |
Discovery of a potent and efficacious peptide derivative for δ/μ opioid agonist/neurokinin 1 antagonist activity with a 2',6'-dimethyl-L-tyrosine: in vitro, in vivo, and NMR-based structural studies. |
Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD |
|
2011 |
Targeting mitochondrial bioenergetics for Alzheimer's prevention and treatment. |
Roberta Diaz Brinton, Ph.D |
|
2011 |
Estrogen protection against mitochondrial toxin-induced cell death in hippocampal neurons: antagonism by progesterone. |
Roberta Diaz Brinton, Ph.D |
|
2011 |
Medroxyprogesterone acetate antagonizes estrogen up-regulation of brain mitochondrial function. |
Roberta Diaz Brinton, Ph.D |
|
2011 |
Novel peptide ligands with dual acting pharmacophores designed for the pathophysiology of neuropathic pain. |
Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD |
|
2011 |
17β-Estradiol regulates insulin-degrading enzyme expression via an ERβ/PI3-K pathway in hippocampus: relevance to Alzheimer's prevention. |
Roberta Diaz Brinton, Ph.D |
|
2011 |
The effect of dietary soy isoflavones before and after ovariectomy on hippocampal protein markers of mitochondrial bioenergetics and antioxidant activity in female monkeys. |
Roberta Diaz Brinton, Ph.D |
|
2011 |
Development of potent μ and δ opioid agonists with high lipophilicity. |
Frank Porreca, PhD, Todd Vanderah, PhD |
|
2011 |
Intrathecal PKA-selective siRNA treatment blocks sustained morphine-mediated pain sensitization and antinociceptive tolerance in rats. |
Tally Largent-Milnes, PhD, Todd Vanderah, PhD |
|
2011 |
Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions. |
Roberta Diaz Brinton, Ph.D |
|
2011 |
Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain. |
John M. Streicher, PhD |
|
2011 |
The role of soy isoflavones in menopausal health: report of The North American Menopause Society/Wulf H. Utian Translational Science Symposium in Chicago, IL (October 2010). |
Roberta Diaz Brinton, Ph.D |
|
2012 |
Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid. |
Roberta Diaz Brinton, Ph.D |
|
2012 |
Estrogen regulation of mitochondrial bioenergetics: implications for prevention of Alzheimer's disease. |
Roberta Diaz Brinton, Ph.D |
|
2012 |
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy. |
John M. Streicher, PhD |
|
2012 |
17β-estradiol and progesterone regulate expression of β-amyloid clearance factors in primary neuron cultures and female rat brain. |
Roberta Diaz Brinton, Ph.D |
|
2012 |
Selective oestrogen receptor modulators differentially potentiate brain mitochondrial function. |
Roberta Diaz Brinton, Ph.D |
