|Title||Regulation of gene expression and mitochondrial dynamics by SMAD.|
|Publication Type||Journal Article|
|Year of Publication||2016|
|Authors||Shah N, Lee NY|
|Journal||Mol Cell Oncol|
Mothers against decapentaplegic homolog (SMAD) proteins exert a wide spectrum of transcriptional effects in different cell types and tissues in response to transforming growth factor-β (TGF-β). A recent study demonstrates what is thought to be the first distinct cytoplasmic function for SMAD2 in modulating mitochondrial dynamics and hence reveals new pathophysiological implications for TGF-β signaling.
|Alternate Journal||Mol Cell Oncol|
|PubMed Central ID||PMC5068171|
|Grant List||R01 CA178443 / CA / NCI NIH HHS / United States|
Regulation of gene expression and mitochondrial dynamics by SMAD.
Faculty Member Reference:
Nam Lee, Ph.D.