May Khanna, PhD

Assistant Professor, Neuroscience - GIDP
Assistant Professor, Pharmacology
Assistant Professor, Member of the Center for Innovation for Brain Science

Contact Information

Office: 460
Building: BRSL
Phone: (520) 626-2147

Email: maykhanna@email.arizona.edu

Research Area:

Molecular and Biochemical Pharmacology

Neuroscience and Pain

Research Interests:

Structure function of alternatively spliced proteins in neuropathic pain.

For more information, please go to https://maykhanna.wixsite.com/themaykhannalab

Publications

2016

(S)-Lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology.

2015

A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors.

(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5.

2014

The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth.

Differential neuroprotective potential of CRMP2 peptide aptamers conjugated to cationic, hydrophobic, and amphipathic cell penetrating peptides.