May Khanna, PhD

Assistant Professor, Neuroscience - GIDP
Assistant Professor, Pharmacology
Assistant Professor, Member of the Center for Innovation for Brain Science

Contact Information

Office: 460
Building: BRSL
Phone: (520) 626-2147

Email: maykhanna@email.arizona.edu

Research Area:

Molecular and Biochemical Pharmacology

Neuroscience and Pain

Research Interests:

Structure function of alternatively spliced proteins in neuropathic pain.

For more information, please go to https://maykhanna.wixsite.com/themaykhannalab

Publications

2016

(S)-Lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology.

2015

A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors.

(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5.

2014

Differential neuroprotective potential of CRMP2 peptide aptamers conjugated to cationic, hydrophobic, and amphipathic cell penetrating peptides.

The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth.