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2015 |
Discovery of Novel Multifunctional Ligands with μ/δ Opioid Agonist/Neurokinin-1 (NK1) Antagonist Activities for the Treatment of Pain. |
Victor Hruby, Ph.D., Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD |
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2015 |
Targeting transporters: promoting blood-brain barrier repair in response to oxidative stress injury. |
Thomas P Davis, PhD, Patrick T Ronaldson, PhD, FAAPS |
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2015 |
CRMP5 Controls Glioblastoma Cell Proliferation and Survival through Notch-Dependent Signaling. |
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2015 |
White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease. |
Roberta Diaz Brinton, Ph.D, Fei Yin, Ph.D. |
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2015 |
Perimenopause as a neurological transition state. |
Roberta Diaz Brinton, Ph.D, Fei Yin, Ph.D. |
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2015 |
Modification of amphipathic non-opioid dynorphin A analogues for rat brain bradykinin receptors. |
Frank Porreca, PhD |
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2015 |
Use of Animal Models in Understanding Cancer-induced Bone Pain. |
Tally Largent-Milnes, PhD, Todd Vanderah, PhD |
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2015 |
Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states. |
Frank Porreca, PhD, Todd Vanderah, PhD |
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2015 |
Orthopedic surgery and bone fracture pain are both significantly attenuated by sustained blockade of nerve growth factor. |
Patrick W Mantyh |
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2015 |
Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. |
John M. Streicher, PhD |
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2015 |
Design, synthesis, and biological evaluation of a series of bifunctional ligands of opioids/SSRIs. |
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2015 |
Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis. |
Todd Vanderah, PhD |
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2015 |
Spinal dopaminergic projections control the transition to pathological pain plasticity via a D1/D5-mediated mechanism. |
Patrick W Mantyh |
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2015 |
Temperature differentially facilitates spontaneous but not evoked glutamate release from cranial visceral primary afferents. |
Tally Largent-Milnes, PhD |
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2015 |
The mixed-action delta/mu opioid agonist MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats, and induces in vitro markers of tolerance and dependence. |
John M. Streicher, PhD |
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2015 |
The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity. |
Roberta Diaz Brinton, Ph.D, Fei Yin, Ph.D. |
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2015 |
Blockade of non-opioid excitatory effects of spinal dynorphin A at bradykinin receptors. |
Frank Porreca, PhD, Todd Vanderah, PhD |
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2015 |
Therapeutic potential of peroxynitrite decomposition catalysts: a patent review. |
Todd Vanderah, PhD |
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2015 |
Discovery of 5-substituted tetrahydronaphthalen-2yl-methyl with N-phenyl-N-(piperidin-4-yl)propionamide derivatives as potent opioid receptor ligands. |
Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD |
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2015 |
Postmenopausal hormone therapy, type 2 diabetes mellitus, and brain volumes. |
Roberta Diaz Brinton, Ph.D |
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2015 |
Association of endogenous sex hormones with adipokines and ghrelin in postmenopausal women. |
Roberta Diaz Brinton, Ph.D |
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2015 |
Epigenetic Regulation of GDF2 Suppresses Anoikis in Ovarian and Breast Epithelia. |
Nam Lee, Ph.D. |
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2015 |
Gemcitabine resistant pancreatic cancer cell lines acquire an invasive phenotype with collateral hypersensitivity to histone deacetylase inhibitors. |
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2015 |
Design and synthesis of novel bivalent ligands (MOR and DOR) by conjugation of enkephalin analogues with 4-anilidopiperidine derivatives. |
Victor Hruby, Ph.D., Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD |
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2014 |
Capsaicin-responsive corneal afferents do not contain TRPV1 at their central terminals in trigeminal nucleus caudalis in rats. |
Tally Largent-Milnes, PhD |
