Arizona Health Sciences

John M. Streicher, PhD

Assistant Professor, Neuroscience - GIDP
Assistant Professor, Pharmacology

Contact Information

Office: Room 563, Life Sciences North
Building: Life Sciences North
Phone: (520) 626-7495

Email: jstreicher@email.arizona.edu

  • BS: George Fox University, 1999
  • MS: Oregon Health and Science University, 2002
  • PhD: University of California – Los Angeles, 2009

Dr. Streicher completed his Ph.D. graduate work at the University of California – Los Angeles in 2009, with a focus on the signal transduction cascades underlying stress response in heart failure. He then joined the lab of Laura Bohn, Ph.D. at The Scripps Research Institute – Florida as a postdoctoral fellow, where he brought his work on signal transduction into the context of opioid receptor signaling and biased agonist drug discovery. He joined the faculty of the University of New England in 2012 as a Research Assistant Professor, promoted to Assistant Professor (tenure track) in 2013. In 2015 he joined the Department of Pharmacology here at the University of Arizona, also as an Assistant Professor (tenure track).

Research Interests: 

Dr. Streicher is interested in understanding the molecular signal transduction cascades downstream of the opioid receptors. His research program focuses on finding new signaling regulators of the opioid receptors, determining their molecular mechanisms, and then determining how these molecular mechanisms result in changes to opioid-induced analgesia and side effects in different pain states. He further uses this information to create novel drug discovery strategies to create new opioid drugs without the side effect drawbacks of current drugs, like addiction. His research approaches encompass the creation of pain states such as post-surgical pain and the measurement of opioid analgesia in these pain states, combined with state-of-the-art approaches to modulate novel signaling regulators in mice including CRISPR/Cas9 in the brain and spinal cord. He also screens drugs in medium- to high-throughput formats in cell models to find and develop new analgesic drugs.

Honors and Awards: 
Travel Award, International Narcotics Research Conference (INRC), June 2015
Travel Award, International Narcotics Research Conference (INRC), July 2014
Abstract (Moses-Fynn et al. 2014) selected for special publicity at the 30th Annual Meeting of the American Academy of Pain Medicine
ASPET Young Scientist Travel Award, Experimental Biology Conference, April 2011
Streicher et al. (2010) (Circulation Research) featured on MDLinx.com, a research indexing site for physicians
Department of Molecular Medicine (DMM) Excellence in Science Award for Best Poster Presentation, DMM Annual Retreat, March 2009
Best Poster Presentation Award, 4th Annual Molecular, Cellular and Integrative Physiology Retreat, March 2008
Graduate With Science Honors, magna cum laude, George Fox University, 1999

 

Publications

2017

2016

2015

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2012

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2002