Arizona Health Sciences

Publications

Year of Publication Title Faculty Association
2015 Discovery of Novel Multifunctional Ligands with μ/δ Opioid Agonist/Neurokinin-1 (NK1) Antagonist Activities for the Treatment of Pain. Victor Hruby, Ph.D., Tally Largent-Milnes, Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD
2015 Epigenetic Regulation of GDF2 Suppresses Anoikis in Ovarian and Breast Epithelia. Nam Lee, Ph.D.
2015 Design, synthesis, and biological evaluation of a series of bifunctional ligands of opioids/SSRIs. Yeon Sun Lee
2015 Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis. Todd Vanderah, PhD
2015 Rapid transport within cerebral perivascular spaces underlies widespread tracer distribution in the brain after intranasal administration. Jeffrey J. Lochhead, PhD
2015 Endoglin Regulation of Smad2 Function Mediates Beclin1 Expression and Endothelial Autophagy. Nam Lee, Ph.D.
2015 Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. John M. Streicher, PhD
2015 Chimeric derivatives of functionalized amino acids and α-aminoamides: compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels. Rajesh Khanna
2015 A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors. Rajesh Khanna, May Khanna, Ph.D., Tally Largent-Milnes, Ph.D., Todd Vanderah, PhD
2015 Therapeutic potential of peroxynitrite decomposition catalysts: a patent review. Todd Vanderah, PhD
2015 Modification of amphipathic non-opioid dynorphin A analogues for rat brain bradykinin receptors. Yeon Sun Lee, Frank Porreca, PhD
2015 Orthopedic surgery and bone fracture pain are both significantly attenuated by sustained blockade of nerve growth factor. Patrick W Mantyh
2015 Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states. Frank Porreca, PhD, Todd Vanderah, PhD
2015 The mixed-action delta/mu opioid agonist MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats, and induces in vitro markers of tolerance and dependence. John M. Streicher, PhD
2015 (S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5. Rajesh Khanna, May Khanna, Ph.D.
2015 Spinal dopaminergic projections control the transition to pathological pain plasticity via a D1/D5-mediated mechanism. Patrick W Mantyh
2015 Temperature differentially facilitates spontaneous but not evoked glutamate release from cranial visceral primary afferents. Tally Largent-Milnes, Ph.D.
2015 Gemcitabine resistant pancreatic cancer cell lines acquire an invasive phenotype with collateral hypersensitivity to histone deacetylase inhibitors. George Watts, Ph.D.
2015 Fn14 receptor promotes invasive potential and metastatic capacity of non-small lung adenocarcinoma cells through the up-regulation of integrin α6. George Watts, Ph.D.
2015 Blockade of non-opioid excitatory effects of spinal dynorphin A at bradykinin receptors. Yeon Sun Lee, Frank Porreca, PhD, Todd Vanderah, PhD
2015 Use of Animal Models in Understanding Cancer-induced Bone Pain. Tally Largent-Milnes, Ph.D., Todd Vanderah, PhD
2014 Src-mediated post-translational regulation of endoglin stability and function is critical for angiogenesis. Nam Lee, Ph.D.
2014 Neuropathic plasticity in the opioid and non-opioid actions of dynorphin A fragments and their interactions with bradykinin B2 receptors on neuronal activity in the rat spinal cord. Yeon Sun Lee, Frank Porreca, PhD
2014 Synthesis and evaluation of bivalent ligands for binding to the human melanocortin-4 receptor. Yeon Sun Lee
2014 Structure-activity relationships of non-opioid [des-Arg(7)]-dynorphin A analogues for bradykinin receptors. Yeon Sun Lee, Frank Porreca, PhD

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