Biblio

Yang J, Betterton RD, Williams EI, Stanton JA, Reddell ES, Ogbonnaya CE, Dorn E, Davis TP, Lochhead JJ, Ronaldson PT.  2022.  High-Dose Acetaminophen Alters the Integrity of the Blood-Brain Barrier and Leads to Increased CNS Uptake of Codeine in Rats.. Pharmaceutics. 14(5)

Betterton RD, Abdullahi W, Williams EI, Lochhead JJ, Brzica H, Stanton J, Reddell E, Ogbonnaya C, Davis TP, Ronaldson PT.  2022.  Regulation of Blood-Brain Barrier Transporters by Transforming Growth Factor-/Activin Receptor-Like Kinase 1 Signaling: Relevance to the Brain Disposition of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors (i.e., Statins).. Drug Metab Dispos. 50(7):942-956.

Kwak E-A, Pan CC, Ramonett A, Kumar S, Cruz-Flores P, Ahmed T, Ortiz HR, Lochhead JJ, Ellis NA, Mouneimne G et al..  2022.  β-spectrin as a stalk cell-intrinsic regulator of VEGF signaling.. Nat Commun. 13(1):1326.

Lochhead JJ, Yang J, Ronaldson PT, Davis TP.  2020.  Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders.. Front Physiol. 11:914.

Lochhead JJ, Ronaldson PT, Davis TP.  2017.  Hypoxic Stress and Inflammatory Pain Disrupt Blood-Brain Barrier Tight Junctions: Implications for Drug Delivery to the Central Nervous System.. AAPS J. 19(4):910-920.

Kumar NN, Gautam M, Lochhead JJ, Wolak DJ, Ithapu V, Singh V, Thorne RG.  2016.  Relative vascular permeability and vascularity across different regions of the rat nasal mucosa: implications for nasal physiology and drug delivery.. Sci Rep. 6:31732.

Lochhead JJ, Wolak DJ, Pizzo ME, Thorne RG.  2015.  Rapid transport within cerebral perivascular spaces underlies widespread tracer distribution in the brain after intranasal administration.. J Cereb Blood Flow Metab. 35(3):371-81.

Lochhead JJ, Thorne RG.  2012.  Intranasal delivery of biologics to the central nervous system.. Adv Drug Deliv Rev. 64(7):614-28.

Lochhead JJ, McCaffrey G, Sanchez-Covarrubias L, Finch JD, DeMarco KM, Quigley CE, Davis TP, Ronaldson PT.  2012.  Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain.. Am J Physiol Heart Circ Physiol. 302(3):H582-93.

Lochhead JJ, McCaffrey G, Quigley CE, Finch J, DeMarco KM, Nametz N, Davis TP.  2010.  Oxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation.. J Cereb Blood Flow Metab. 30(9):1625-36.

McCaffrey G, Willis CL, Staatz WD, Nametz N, Quigley CA, Hom S, Lochhead JJ, Davis TP.  2009.  Occludin oligomeric assemblies at tight junctions of the blood-brain barrier are altered by hypoxia and reoxygenation stress.. J Neurochem. 110(1):58-71.