Biblio
Found 20 results
Filters: Author is Lai, Josephine [Clear All Filters]
Cyclic non-opioid dynorphin A analogues for the bradykinin receptors.. Bioorg Med Chem Lett. 26(22):5513-5516.
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2016. Discovery of Stable Non-opioid Dynorphin A Analogues Interacting at the Bradykinin Receptors for the Treatment of Neuropathic Pain.. ACS Chem Neurosci. 7(12):1746-1752.
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2016. Enkephalin analogues with N-phenyl-N-(piperidin-2-ylmethyl)propionamide derivatives: Synthesis and biological evaluations.. Bioorg Med Chem Lett. 26(1):222-7.
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2016. Various modifications of the amphipathic dynorphin A pharmacophore for rat brain bradykinin receptors.. Chem Biol Drug Des. 88(4):615-9.
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2016. Blockade of non-opioid excitatory effects of spinal dynorphin A at bradykinin receptors.. Receptors Clin Investig. 2(1)
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2015. Design and synthesis of novel bivalent ligands (MOR and DOR) by conjugation of enkephalin analogues with 4-anilidopiperidine derivatives.. Bioorg Med Chem Lett. 25(20):4683-8.
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2015. Design, synthesis, and biological evaluation of a series of bifunctional ligands of opioids/SSRIs.. Bioorg Med Chem. 23(6):1251-9.
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2015. Discovery of 5-substituted tetrahydronaphthalen-2yl-methyl with N-phenyl-N-(piperidin-4-yl)propionamide derivatives as potent opioid receptor ligands.. Bioorg Med Chem. 23(18):6185-94.
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2015. Modification of amphipathic non-opioid dynorphin A analogues for rat brain bradykinin receptors.. Bioorg Med Chem Lett. 25(1):30-3.
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2015. Discovery of amphipathic dynorphin A analogues to inhibit the neuroexcitatory effects of dynorphin A through bradykinin receptors in the spinal cord.. J Am Chem Soc. 136(18):6608-16.
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2014. Neuropathic plasticity in the opioid and non-opioid actions of dynorphin A fragments and their interactions with bradykinin B2 receptors on neuronal activity in the rat spinal cord.. Neuropharmacology. 85:375-83.
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2014. Structure-activity relationships of non-opioid [des-Arg(7)]-dynorphin A analogues for bradykinin receptors.. Bioorg Med Chem Lett. 24(21):4976-9.
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2014. Effect of anchoring 4-anilidopiperidines to opioid peptides.. Bioorg Med Chem Lett. 23(11):3434-7.
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2013. Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities.. Bioorg Med Chem Lett. 23(17):4975-8.
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2013. Development of potent μ and δ opioid agonists with high lipophilicity.. J Med Chem. 54(1):382-6.
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2011. Discovery of a potent and efficacious peptide derivative for δ/μ opioid agonist/neurokinin 1 antagonist activity with a 2',6'-dimethyl-L-tyrosine: in vitro, in vivo, and NMR-based structural studies.. J Med Chem. 54(7):2029-38.
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2011. Novel peptide ligands with dual acting pharmacophores designed for the pathophysiology of neuropathic pain.. Brain Res. 1395:1-11.
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2011. Synthesis and biological evaluation of new opioid agonist and neurokinin-1 antagonist bivalent ligands.. Bioorg Med Chem. 19(20):6135-42.
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2011. Novel bifunctional peptides as opioid agonists and NK-1 antagonists.. Adv Exp Med Biol. 611:537-8.
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2009. Novel D-amino acid tetrapeptides produce potent antinociception by selectively acting at peripheral kappa-opioid receptors.. Eur J Pharmacol. 583(1):62-72.
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