Biblio

Nilles KL, Williams EI, Betterton RD, Davis TP, Ronaldson PT.  2022.  Blood-Brain Barrier Transporters: Opportunities for Therapeutic Development in Ischemic Stroke.. Int J Mol Sci. 23(3)

Yang J, Betterton RD, Williams EI, Stanton JA, Reddell ES, Ogbonnaya CE, Dorn E, Davis TP, Lochhead JJ, Ronaldson PT.  2022.  High-Dose Acetaminophen Alters the Integrity of the Blood-Brain Barrier and Leads to Increased CNS Uptake of Codeine in Rats.. Pharmaceutics. 14(5)

Betterton RD, Abdullahi W, Williams EI, Lochhead JJ, Brzica H, Stanton J, Reddell E, Ogbonnaya C, Davis TP, Ronaldson PT.  2022.  Regulation of Blood-Brain Barrier Transporters by Transforming Growth Factor-/Activin Receptor-Like Kinase 1 Signaling: Relevance to the Brain Disposition of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors (i.e., Statins).. Drug Metab Dispos. 50(7):942-956.

Stanton JA, Williams EI, Betterton RD, Davis TP, Ronaldson PT.  2022.  Targeting organic cation transporters at the blood-brain barrier to treat ischemic stroke in rats.. Exp Neurol. 357:114181.

Ronaldson PT, Davis TP.  2022.  Transport Mechanisms at the Blood-Brain Barrier and in Cellular Compartments of the Neurovascular Unit: Focus on CNS Delivery of Small Molecule Drugs.. Pharmaceutics. 14(7)

Lyden PD, Pryor KE, Minigh J, Davis TP, Griffin JH, Levy H, Zlokovic BV.  2021.  Stroke Treatment With PAR-1 Agents to Decrease Hemorrhagic Transformation.. Front Neurol. 12:593582.

Ronaldson PT, Brzica H, Abdullahi W, Reilly BG, Davis TP.  2021.  Transport Properties of Statins by Organic Anion Transporting Polypeptide 1A2 and Regulation by Transforming Growth Factor- Signaling in Human Endothelial Cells.. J Pharmacol Exp Ther. 376(2):148-160.

Liktor-Busa E, Blawn KT, Kellohen KL, Wiese BM, Verkhovsky V, Wahl J, Vivek A, Palomino SM, Davis TP, Vanderah TW et al..  2020.  Functional NHE1 expression is critical to blood brain barrier integrity and sumatriptan blood to brain uptake.. PLoS One. 15(5):e0227463.

Ronaldson PT, Davis TP.  2020.  Regulation of blood-brain barrier integrity by microglia in health and disease: A therapeutic opportunity.. J Cereb Blood Flow Metab. 40(1_suppl):S6-S24.

Lochhead JJ, Yang J, Ronaldson PT, Davis TP.  2020.  Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders.. Front Physiol. 11:914.

Williams EI, Betterton RD, Davis TP, Ronaldson PT.  2020.  Transporter-Mediated Delivery of Small Molecule Drugs to the Brain: A Critical Mechanism That Can Advance Therapeutic Development for Ischemic Stroke.. Pharmaceutics. 12(2)

Cottier KE, Galloway EA, Calabrese EC, Tome ME, Liktor-Busa E, Kim J, Davis TP, Vanderah TW, Largent-Milnes TM.  2018.  Loss of Blood-Brain Barrier Integrity in a KCl-Induced Model of Episodic Headache Enhances CNS Drug Delivery.. eNeuro. 5(4)

Abdullahi W, Brzica H, Ibbotson K, Davis TP, Ronaldson PT.  2017.  Bone morphogenetic protein-9 increases the functional expression of organic anion transporting polypeptide 1a4 at the blood-brain barrier via the activin receptor-like kinase-1 receptor.. J Cereb Blood Flow Metab. 37(7):2340-2345.

Abdullahi W, Davis TP, Ronaldson PT.  2017.  Functional Expression of P-glycoprotein and Organic Anion Transporting Polypeptides at the Blood-Brain Barrier: Understanding Transport Mechanisms for Improved CNS Drug Delivery? AAPS J. 19(4):931-939.

Lochhead JJ, Ronaldson PT, Davis TP.  2017.  Hypoxic Stress and Inflammatory Pain Disrupt Blood-Brain Barrier Tight Junctions: Implications for Drug Delivery to the Central Nervous System.. AAPS J. 19(4):910-920.

Ronaldson PT, Davis TP.  2015.  Targeting transporters: promoting blood-brain barrier repair in response to oxidative stress injury.. Brain Res. 1623:39-52.

Lochhead JJ, McCaffrey G, Sanchez-Covarrubias L, Finch JD, DeMarco KM, Quigley CE, Davis TP, Ronaldson PT.  2012.  Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain.. Am J Physiol Heart Circ Physiol. 302(3):H582-93.

Lochhead JJ, McCaffrey G, Quigley CE, Finch J, DeMarco KM, Nametz N, Davis TP.  2010.  Oxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation.. J Cereb Blood Flow Metab. 30(9):1625-36.

McCaffrey G, Willis CL, Staatz WD, Nametz N, Quigley CA, Hom S, Lochhead JJ, Davis TP.  2009.  Occludin oligomeric assemblies at tight junctions of the blood-brain barrier are altered by hypoxia and reoxygenation stress.. J Neurochem. 110(1):58-71.