Biblio

Found 22 results
Filters: Author is Streicher, John M and Keyword is Mice  [Clear All Filters]
2025
Seekins CA, Welborn AM, Schwarz AM, Streicher JM.  2025.  Select terpenes from Cannabis sativa are antinociceptive in mouse models of post-operative pain and fibromyalgia via adenosine A receptors.. Pharmacol Rep. 77(1):172-181.
Schwarz AM, Seekins CA, El-Sissi O, Streicher JM.  2025.  Terpene blends from Cannabis sativa are cannabimimetic and antinociceptive in a mouse chronic neuropathic pain model via activation of adenosine A receptors.. Neurosci Lett. 854:138205.
2024
Duron DI, Tanguturi P, Campbell CS, Chou K, Bejarano P, Gabriel KA, Bowden JL, Mishra S, Brackett C, Barlow D et al..  2024.  Inhibiting spinal cord-specific hsp90 isoforms reveals a novel strategy to improve the therapeutic index of opioid treatment.. Sci Rep. 14(1):14715.
Schwarz AM, Kobeci D, Mancuso JA, Moreno-Rodríguez V, Seekins C, Bui T, Welborn A, Carr J, Streicher JM.  2024.  Select Minor Cannabinoids from Are Cannabimimetic and Antinociceptive in a Mouse Model of Chronic Neuropathic Pain.. J Pharmacol Exp Ther. 391(2):214-221.
2023
Gabriel KA, Streicher JM.  2023.  HSP90 inhibition in the mouse spinal cord enhances opioid signaling by suppressing an AMPK-mediated negative feedback loop.. Sci Signal. 16(780):eade2438.
2022
Keresztes A, Olson K, Nguyen P, Lopez-Pier MA, Hecksel R, Barker NK, Liu Z, Hruby V, Konhilas J, Langlais PR et al..  2022.  Antagonism of the mu-delta opioid receptor heterodimer enhances opioid antinociception by activating Src and calcium/calmodulin-dependent protein kinase II signaling.. Pain. 163(1):146-158.
2021
LaVigne JE, Hecksel R, Keresztes A, Streicher JM.  2021.  Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity.. Sci Rep. 11(1):8232.
2020
Duron DI, Hanak F, Streicher JM.  2020.  Daily intermittent fasting in mice enhances morphine-induced antinociception while mitigating reward, tolerance, and constipation.. Pain. 161(10):2353-2363.
Stine C, Coleman DL, Flohrschutz AT, Thompson AL, Mishra S, Blagg BS, Largent-Milnes TM, Lei W, Streicher JM.  2020.  Heat shock protein 90 inhibitors block the antinociceptive effects of opioids in mouse chemotherapy-induced neuropathy and cancer bone pain models.. Pain. 161(8):1798-1807.
Duron DI, Lei W, Barker NK, Stine C, Mishra S, Blagg BSJ, Langlais PR, Streicher JM.  2020.  Inhibition of Hsp90 in the spinal cord enhances the antinociceptive effects of morphine by activating an ERK-RSK pathway.. Sci Signal. 13(630)
Lei W, Vekariya RH, Ananthan S, Streicher JM.  2020.  A Novel Mu-Delta Opioid Agonist Demonstrates Enhanced Efficacy With Reduced Tolerance and Dependence in Mouse Neuropathic Pain Models.. J Pain. 21(1-2):146-160.
2019
Olson KM, Duron DI, Womer D, Fell R, Streicher JM.  2019.  Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids.. PLoS One. 14(6):e0217371.
2018
Edwards KA, Havelin JJ, McIntosh MI, Ciccone HA, Pangilinan K, Imbert I, Largent-Milnes TM, King T, Vanderah TW, Streicher JM.  2018.  A Kappa Opioid Receptor Agonist Blocks Bone Cancer Pain Without Altering Bone Loss, Tumor Size, or Cancer Cell Proliferation in a Mouse Model of Cancer-Induced Bone Pain.. J Pain. 19(6):612-625.
Olson KM, Keresztes A, Tashiro JK, Daconta LV, Hruby VJ, Streicher JM.  2018.  Synthesis and Evaluation of a Novel Bivalent Selective Antagonist for the Mu-Delta Opioid Receptor Heterodimer that Reduces Morphine Withdrawal in Mice.. J Med Chem. 61(14):6075-6086.
Shah N, Kumar S, Zaman N, Pan CC, Bloodworth JC, Lei W, Streicher JM, Hempel N, Mythreye K, Lee NY.  2018.  TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth.. Nat Commun. 9(1):1696.
2017
Lei W, Mullen N, McCarthy S, Brann C, Richard P, Cormier J, Edwards K, Bilsky EJ, Streicher JM.  2017.  Heat-shock protein 90 (Hsp90) promotes opioid-induced anti-nociception by an ERK mitogen-activated protein kinase (MAPK) mechanism in mouse brain.. J Biol Chem. 292(25):10414-10428.
2016
Zhang Y, Williams DA, Zaidi SA, Yuan Y, Braithwaite A, Bilsky EJ, Dewey WL, Akbarali HI, Streicher JM, Selley DE.  2016.  17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-(4'-pyridylcarboxamido)morphinan (NAP) Modulating the Mu Opioid Receptor in a Biased Fashion.. ACS Chem Neurosci. 7(3):297-304.
2013
Zhou L, Lovell KM, Frankowski KJ, Slauson SR, Phillips AM, Streicher JM, Stahl E, Schmid CL, Hodder P, Madoux F et al..  2013.  Development of functionally selective, small molecule agonists at kappa opioid receptors.. J Biol Chem. 288(51):36703-16.
Schmid CL, Streicher JM, Groer CE, Munro TA, Zhou L, Bohn LM.  2013.  Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at κ-opioid receptors in striatal neurons.. J Biol Chem. 288(31):22387-98.
2011
Tarselli MA, Raehal KM, Brasher AK, Streicher JM, Groer CE, Cameron MD, Bohn LM, Micalizio GC.  2011.  Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain.. Nat Chem. 3(6):449-53.
2010
Streicher JM, Ren S, Herschman H, Wang Y.  2010.  MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart.. Circ Res. 106(8):1434-43.
Papanicolaou KN, Streicher JM, Ishikawa T-O, Herschman H, Wang Y, Walsh K.  2010.  Preserved heart function and maintained response to cardiac stresses in a genetic model of cardiomyocyte-targeted deficiency of cyclooxygenase-2.. J Mol Cell Cardiol. 49(2):196-209.