Biblio

Found 32 results
Filters: Keyword is Alzheimer Disease  [Clear All Filters]
2023
Mi Y, Qi G, Vitali F, Shang Y, Raikes AC, Wang T, Jin Y, Brinton RD, Gu H, Yin F.  2023.  Loss of fatty acid degradation by astrocytic mitochondria triggers neuroinflammation and neurodegeneration.. Nat Metab. 5(3):445-465.
2022
McLean JW, Bhattrai A, Vitali F, Raikes AC, Wiegand J-PL, Brinton RDiaz.  2022.  Contributions of sex and genotype to exploratory behavior differences in an aged humanized mouse model of late-onset Alzheimer's disease.. Learn Mem. 29(9):321-331.
Mishra A, Wang Y, Yin F, Vitali F, Rodgers KE, Soto M, Mosconi L, Wang T, Brinton RD.  2022.  A tale of two systems: Lessons learned from female mid-life aging with implications for Alzheimer's prevention & treatment.. Ageing Res Rev. 74:101542.
2017
Zissimopoulos JM, Barthold D, Brinton RDiaz, Joyce G.  2017.  Sex and Race Differences in the Association Between Statin Use and the Incidence of Alzheimer Disease.. JAMA Neurol. 74(2):225-232.
2016
Zhang L, Trushin S, Christensen TA, Bachmeier BV, Gateno B, Schroeder A, Yao J, Itoh K, Sesaki H, Poon WW et al..  2016.  Altered brain energetics induces mitochondrial fission arrest in Alzheimer's Disease.. Sci Rep. 6:18725.
Rettberg JR, Dang H, Hodis HN, Henderson VW, St John JA, Mack WJ, Brinton RDiaz.  2016.  Identifying postmenopausal women at risk for cognitive decline within a healthy cohort using a panel of clinical metabolic indicators: potential for detecting an at-Alzheimer's risk metabolic phenotype.. Neurobiol Aging. 40:155-63.
Zhao L, Mao Z, Woody SK, Brinton RD.  2016.  Sex differences in metabolic aging of the brain: insights into female susceptibility to Alzheimer's disease.. Neurobiol Aging. 42:69-79.
2015
Yin F, Yao J, Sancheti H, Feng T, Melcangi RC, Morgan TE, Finch CE, Pike CJ, Mack WJ, Cadenas E et al..  2015.  The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity.. Neurobiol Aging. 36(7):2282-2295.
Caldwell CC, Yao J, Brinton RDiaz.  2015.  Targeting the prodromal stage of Alzheimer's disease: bioenergetic and mitochondrial opportunities.. Neurotherapeutics. 12(1):66-80.
Klosinski LP, Yao J, Yin F, Fonteh AN, Harrington MG, Christensen TA, Trushina E, Brinton RDiaz.  2015.  White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease.. EBioMedicine. 2(12):1888-904.
2014
Sancheti H, Patil I, Kanamori K, Brinton RDiaz, Zhang W, Lin A-L, Cadenas E.  2014.  Hypermetabolic state in the 7-month-old triple transgenic mouse model of Alzheimer's disease and the effect of lipoic acid: a 13C-NMR study.. J Cereb Blood Flow Metab. 34(11):1749-60.
Sancheti H, Kanamori K, Patil I, Brinton RDiaz, Ross BD, Cadenas E.  2014.  Reversal of metabolic deficits by lipoic acid in a triple transgenic mouse model of Alzheimer's disease: a 13C NMR study.. J Cereb Blood Flow Metab. 34(2):288-96.
2013
Ding F, Yao J, Rettberg JR, Chen S, Brinton RDiaz.  2013.  Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.. PLoS One. 8(11):e79977.
Zhao L, Mao Z, Chen S, Schneider LS, Brinton RD.  2013.  Early intervention with an estrogen receptor β-selective phytoestrogenic formulation prolongs survival, improves spatial recognition memory, and slows progression of amyloid pathology in a female mouse model of Alzheimer's disease.. J Alzheimers Dis. 37(2):403-19.
Brinton RD.  2013.  Neurosteroids as regenerative agents in the brain: therapeutic implications.. Nat Rev Endocrinol. 9(4):241-50.
Ding F, Yao J, Zhao L, Mao Z, Chen S, Brinton RDiaz.  2013.  Ovariectomy induces a shift in fuel availability and metabolism in the hippocampus of the female transgenic model of familial Alzheimer's.. PLoS One. 8(3):e59825.
Singh M, Simpkins JW, Simpkins JW, Bimonte-Nelson HA, Bimonte-Nelson HA, Brinton RDiaz.  2013.  Window of opportunity for estrogen and progestin intervention in brain aging and Alzheimer's disease.. Brain Res. 1514:1-2.
2012
Yao J, Brinton RDiaz.  2012.  Estrogen regulation of mitochondrial bioenergetics: implications for prevention of Alzheimer's disease.. Adv Pharmacol. 64:327-71.
Yao J, Irwin R, Chen S, Hamilton R, Cadenas E, Brinton RDiaz.  2012.  Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid.. Neurobiol Aging. 33(8):1507-21.
2011
Zhao L, Yao J, Mao Z, Chen S, Wang Y, Brinton RDiaz.  2011.  17β-Estradiol regulates insulin-degrading enzyme expression via an ERβ/PI3-K pathway in hippocampus: relevance to Alzheimer's prevention.. Neurobiol Aging. 32(11):1949-63.
Yao J, Chen S, Mao Z, Cadenas E, Brinton RDiaz.  2011.  2-Deoxy-D-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease.. PLoS One. 6(7):e21788.
Yao J, Rettberg JR, Klosinski LP, Cadenas E, Brinton RDiaz.  2011.  Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions.. Mol Aspects Med. 32(4-6):247-57.
Yao J, Brinton RDiaz.  2011.  Targeting mitochondrial bioenergetics for Alzheimer's prevention and treatment.. Curr Pharm Des. 17(31):3474-9.
2010
Yao J, Hamilton RT, Cadenas E, Brinton RDiaz.  2010.  Decline in mitochondrial bioenergetics and shift to ketogenic profile in brain during reproductive senescence.. Biochim Biophys Acta. 1800(10):1121-6.
Henderson VW, Brinton RDiaz.  2010.  Menopause and mitochondria: windows into estrogen effects on Alzheimer's disease risk and therapy.. Prog Brain Res. 182:77-96.

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