Edita Navratilova

Associate Professor, Pharmacology
Member of the Graduate Faculty

Contact Information

Office: 517
Building: Life Sciences North
Phone: (520) 626-4381

Email: edita@arizona.edu

Research Interests:

Neuropharmacology of pain; brain circuits for pain, relief of pain and reward; opioid neurotransmission; mechanisms of acute and chronic pain.

Publications

2023

Chronic pain recruits hypothalamic dynorphin/kappa opioid receptor signalling to promote wakefulness and vigilance.

2022

Exploring the neurobiology of the premonitory phase of migraine preclinically - a role for hypothalamic kappa opioid receptors?

Preclinical assessment of onabotulinumtoxinA for the treatment of mild traumatic brain injury-related acute and persistent post-traumatic headache.

A prolactin-dependent sexually dimorphic mechanism of migraine chronification.

Dysregulation of serum prolactin links the hypothalamus with female nociceptors to promote migraine.

Kappa Opioid Receptor Blockade in the Amygdala Mitigates Pain Like-Behaviors by Inhibiting Corticotropin Releasing Factor Neurons in a Rat Model of Functional Pain.

2021

Decreased dopaminergic inhibition of pyramidal neurons in anterior cingulate cortex maintains chronic neuropathic pain.

2013

Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities.

2009

Novel bifunctional peptides as opioid agonists and NK-1 antagonists.