Josephine Lai , Ph.D.

Professor Emerita, Professor of Pharmacology and Molecular and Cellular Biology

Contact Information

Phone: (520) 626-2147

Email: lai@email.arizona.edu
Research Interests: 

Molecular mechanisms of neuropathic pain; opioid receptor pharmacology; gene targeting, drug discovery.

 

Publications

2014

Discovery of amphipathic dynorphin A analogues to inhibit the neuroexcitatory effects of dynorphin A through bradykinin receptors in the spinal cord.

2013

Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities.

Effect of anchoring 4-anilidopiperidines to opioid peptides.

2011

Synthesis and biological evaluation of new opioid agonist and neurokinin-1 antagonist bivalent ligands.