| Title | Regulation of gene expression and mitochondrial dynamics by SMAD. |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Shah N, Lee NY |
| Journal | Mol Cell Oncol |
| Volume | 3 |
| Issue | 5 |
| Pagination | e1204492 |
| Date Published | 2016 |
| ISSN | 2372-3556 |
| Abstract | Mothers against decapentaplegic homolog (SMAD) proteins exert a wide spectrum of transcriptional effects in different cell types and tissues in response to transforming growth factor-β (TGF-β). A recent study demonstrates what is thought to be the first distinct cytoplasmic function for SMAD2 in modulating mitochondrial dynamics and hence reveals new pathophysiological implications for TGF-β signaling. |
| DOI | 10.1080/23723556.2016.1204492 |
| Alternate Journal | Mol Cell Oncol |
| PubMed ID | 27857972 |
| PubMed Central ID | PMC5068171 |
| Grant List | R01 CA178443 / CA / NCI NIH HHS / United States |
Faculty Member Reference:
Nam Lee, Ph.D.