Biblio

Martin LF, Cheng K, Washington SM, Denton M, Goel V, Khandekar M, Largent-Milnes TM, Patwardhan A, Ibrahim MM.  2023.  Green Light Exposure Elicits Anti-inflammation, Endogenous Opioid Release and Dampens Synaptic Potentiation to Relieve Post-surgical Pain.. J Pain. 24(3):509-529.

Blackwell JA, Silva JF, Louis EM, Savu A, Largent-Milnes TM, Brooks HL, Pires PW.  2022.  Cerebral arteriolar and neurovascular dysfunction after chemically induced menopause in mice.. Am J Physiol Heart Circ Physiol. 323(5):H845-H860.

Bartolo ND, Reid SE, Krishnan HS, Haseki A, Renganathan M, Largent-Milnes TM, Norwood BA, Loggia ML, Hooker JM.  2022.  Radiocaine: An Imaging Marker of Neuropathic Injury.. ACS Chem Neurosci. 13(24):3661-3667.

Vizcarra VS, Barber KR, Franca-Solomon G, Majuta L, Smith A, Langlais PR, Largent-Milnes TM, Vanderah TW, Riegel AC.  2022.  Targeting 5-HT receptors and Kv7 channels in PFC to attenuate chronic neuropathic pain in rats using a spared nerve injury model.. Neurosci Lett. 789:136864.

Doyle TM, Janes K, Chen Z, Grace PM, Esposito E, Cuzzocrea S, Largent-Milnes TM, Neumann WL, Watkins LR, Spiegel S et al..  2020.  Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents.. Pain. 161(9):2107-2118.

Liktor-Busa E, Blawn KT, Kellohen KL, Wiese BM, Verkhovsky V, Wahl J, Vivek A, Palomino SM, Davis TP, Vanderah TW et al..  2020.  Functional NHE1 expression is critical to blood brain barrier integrity and sumatriptan blood to brain uptake.. PLoS One. 15(5):e0227463.

Zhang H, Largent-Milnes TM, Vanderah TW.  2020.  Glial neuroimmune signaling in opioid reward.. Brain Res Bull. 155:102-111.

Stine C, Coleman DL, Flohrschutz AT, Thompson AL, Mishra S, Blagg BS, Largent-Milnes TM, Lei W, Streicher JM.  2020.  Heat shock protein 90 inhibitors block the antinociceptive effects of opioids in mouse chemotherapy-induced neuropathy and cancer bone pain models.. Pain. 161(8):1798-1807.

Thompson AL, Largent-Milnes TM, Vanderah TW.  2019.  Animal Models for the Study of Bone-Derived Pain.. Methods Mol Biol. 1914:391-407.

Hay M, Polt R, Heien ML, Vanderah TW, Largent-Milnes TM, Rodgers K, Falk T, Bartlett MJ, Doyle KP, Konhilas JP.  2019.  A Novel Angiotensin-(1-7) Glycosylated Mas Receptor Agonist for Treating Vascular Cognitive Impairment and Inflammation-Related Memory Dysfunction.. J Pharmacol Exp Ther. 369(1):9-25.

Chen Z, Doyle TM, Luongo L, Largent-Milnes TM, Giancotti LAntonio, Kolar G, Squillace S, Boccella S, Walker JK, Pendleton A et al..  2019.  Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain.. Proc Natl Acad Sci U S A. 116(21):10557-10562.

Pandit V, Khan M, Zakaria ERasheid, Largent-Milnes TM, Hamidi M, O'Keeffe T, Vanderah TW, Joseph B.  2018.  Continuous remote ischemic conditioning attenuates cognitive and motor deficits from moderate traumatic brain injury.. J Trauma Acute Care Surg. 85(1):48-53.

Edwards KA, Havelin JJ, McIntosh MI, Ciccone HA, Pangilinan K, Imbert I, Largent-Milnes TM, King T, Vanderah TW, Streicher JM.  2018.  A Kappa Opioid Receptor Agonist Blocks Bone Cancer Pain Without Altering Bone Loss, Tumor Size, or Cancer Cell Proliferation in a Mouse Model of Cancer-Induced Bone Pain.. J Pain. 19(6):612-625.

Cottier KE, Galloway EA, Calabrese EC, Tome ME, Liktor-Busa E, Kim J, Davis TP, Vanderah TW, Largent-Milnes TM.  2018.  Loss of Blood-Brain Barrier Integrity in a KCl-Induced Model of Episodic Headache Enhances CNS Drug Delivery.. eNeuro. 5(4)

Zhang H, Lund DM, Ciccone HA, Staatz WD, Ibrahim MM, Largent-Milnes TM, Seltzman HH, Spigelman I, Vanderah TW.  2018.  Peripherally restricted cannabinoid 1 receptor agonist as a novel analgesic in cancer-induced bone pain.. Pain. 159(9):1814-1823.

Deekonda S, Cole J, Sunna S, Rankin D, Largent-Milnes TM, Davis P, BassiriRad NM, Lai J, Vanderah TW, Porecca F et al..  2016.  Enkephalin analogues with N-phenyl-N-(piperidin-2-ylmethyl)propionamide derivatives: Synthesis and biological evaluations.. Bioorg Med Chem Lett. 26(1):222-7.

Ramos-Colon CN, Lee YSun, Remesic M, Hall SM, LaVigne J, Davis P, Sandweiss AJ, McIntosh MI, Hanson J, Largent-Milnes TM et al..  2016.  Structure-Activity Relationships of [des-Arg(7)]Dynorphin A Analogues at the κ Opioid Receptor.. J Med Chem. 59(22):10291-10298.

Deekonda S, Wugalter L, Rankin D, Largent-Milnes TM, Davis P, Wang Y, BassiriRad NM, Lai J, Kulkarni V, Vanderah TW et al..  2015.  Design and synthesis of novel bivalent ligands (MOR and DOR) by conjugation of enkephalin analogues with 4-anilidopiperidine derivatives.. Bioorg Med Chem Lett. 25(20):4683-8.

Deekonda S, Wugalter L, Kulkarni V, Rankin D, Largent-Milnes TM, Davis P, BassiriRad NM, Lai J, Vanderah TW, Porreca F et al..  2015.  Discovery of 5-substituted tetrahydronaphthalen-2yl-methyl with N-phenyl-N-(piperidin-4-yl)propionamide derivatives as potent opioid receptor ligands.. Bioorg Med Chem. 23(18):6185-94.

Giri AKumar, Apostol CR, Wang Y, Forte BL, Largent-Milnes TM, Davis P, Rankin D, Molnar G, Olson KM, Porreca F et al..  2015.  Discovery of Novel Multifunctional Ligands with μ/δ Opioid Agonist/Neurokinin-1 (NK1) Antagonist Activities for the Treatment of Pain.. J Med Chem. 58(21):8573-83.

Fawley JA, Hofmann ME, Largent-Milnes TM, Andresen MC.  2015.  Temperature differentially facilitates spontaneous but not evoked glutamate release from cranial visceral primary afferents.. PLoS One. 10(5):e0127764.

Hegarty DM, Hermes SM, Largent-Milnes TM, Aicher SA.  2014.  Capsaicin-responsive corneal afferents do not contain TRPV1 at their central terminals in trigeminal nucleus caudalis in rats.. J Chem Neuroanat. 61-62:1-12.

Hofmann ME, Largent-Milnes TM, Fawley JA, Andresen MC.  2014.  External QX-314 inhibits evoked cranial primary afferent synaptic transmission independent of TRPV1.. J Neurophysiol. 112(11):2697-706.

Largent-Milnes TM, Hegarty DM, Aicher SA, Andresen MC.  2014.  Physiological temperatures drive glutamate release onto trigeminal superficial dorsal horn neurons.. J Neurophysiol. 111(11):2222-31.

Lozano-Ondoua AN, Hanlon KE, Symons-Liguori AM, Largent-Milnes TM, Havelin JJ, Ferland HL, Chandramouli A, Owusu-Ankomah M, Nikolich-Zugich T, Bloom AP et al..  2013.  Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists.. J Bone Miner Res. 28(1):92-107.