Biblio

Ibbotson K, Yell J, Ronaldson PT.  2017.  Nrf2 signaling increases expression of ATP-binding cassette subfamily C mRNA transcripts at the blood-brain barrier following hypoxia-reoxygenation stress.. Fluids Barriers CNS. 14(1):6.

Zhang L, Trushin S, Christensen TA, Bachmeier BV, Gateno B, Schroeder A, Yao J, Itoh K, Sesaki H, Poon WW et al..  2016.  Altered brain energetics induces mitochondrial fission arrest in Alzheimer's Disease.. Sci Rep. 6:18725.

Irwin RW, Solinsky CM, Loya CM, Salituro FG, Rodgers KE, Bauer G, Rogawski MA, Brinton RDiaz.  2015.  Allopregnanolone preclinical acute pharmacokinetic and pharmacodynamic studies to predict tolerability and efficacy for Alzheimer's disease.. PLoS One. 10(6):e0128313.

Klosinski LP, Yao J, Yin F, Fonteh AN, Harrington MG, Christensen TA, Trushina E, Brinton RDiaz.  2015.  White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease.. EBioMedicine. 2(12):1888-904.

Sancheti H, Patil I, Kanamori K, Brinton RDiaz, Zhang W, Lin A-L, Cadenas E.  2014.  Hypermetabolic state in the 7-month-old triple transgenic mouse model of Alzheimer's disease and the effect of lipoic acid: a 13C-NMR study.. J Cereb Blood Flow Metab. 34(11):1749-60.

Bannister K, Lee YSun, Goncalves L, Porreca F, Lai J, Dickenson AH.  2014.  Neuropathic plasticity in the opioid and non-opioid actions of dynorphin A fragments and their interactions with bradykinin B2 receptors on neuronal activity in the rat spinal cord.. Neuropharmacology. 85:375-83.

Sancheti H, Akopian G, Yin F, Brinton RD, Walsh JP, Cadenas E.  2013.  Age-dependent modulation of synaptic plasticity and insulin mimetic effect of lipoic acid on a mouse model of Alzheimer's disease.. PLoS One. 8(7):e69830.

Lozano-Ondoua AN, Symons-Liguori AM, Vanderah TW.  2013.  Cancer-induced bone pain: Mechanisms and models.. Neurosci Lett. 557 Pt A:52-9.

Ding F, Yao J, Rettberg JR, Chen S, Brinton RDiaz.  2013.  Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.. PLoS One. 8(11):e79977.

Zhao L, Mao Z, Chen S, Schneider LS, Brinton RD.  2013.  Early intervention with an estrogen receptor β-selective phytoestrogenic formulation prolongs survival, improves spatial recognition memory, and slows progression of amyloid pathology in a female mouse model of Alzheimer's disease.. J Alzheimers Dis. 37(2):403-19.

Podolsky AT, Sandweiss A, Hu J, Bilsky EJ, Cain JP, Kumirov VK, Lee YSun, Hruby VJ, Vardanyan RS, Vanderah TW.  2013.  Novel fentanyl-based dual μ/δ-opioid agonists for the treatment of acute and chronic pain.. Life Sci. 93(25-26):1010-6.

Ding F, Yao J, Zhao L, Mao Z, Chen S, Brinton RDiaz.  2013.  Ovariectomy induces a shift in fuel availability and metabolism in the hippocampus of the female transgenic model of familial Alzheimer's.. PLoS One. 8(3):e59825.

Sun C, Ou X, Farley JM, Stockmeier C, Bigler S, Brinton RDiaz, Wang JMing.  2012.  Allopregnanolone increases the number of dopaminergic neurons in substantia nigra of a triple transgenic mouse model of Alzheimer's disease.. Curr Alzheimer Res. 9(4):473-80.

Adeosun SO, Hou X, Jiao Y, Zheng B, Henry S, Hill R, He Z, Pani A, Kyle P, Ou X et al..  2012.  Allopregnanolone reinstates tyrosine hydroxylase immunoreactive neurons and motor performance in an MPTP-lesioned mouse model of Parkinson's disease.. PLoS One. 7(11):e50040.

Pajouhesh H, Feng Z-P, Zhang L, Pajouhesh H, Jiang X, Hendricson A, Dong H, Tringham E, Ding Y, Vanderah TW et al..  2012.  Structure-activity relationships of trimethoxybenzyl piperazine N-type calcium channel inhibitors.. Bioorg Med Chem Lett. 22(12):4153-8.

Yao J, Chen S, Mao Z, Cadenas E, Brinton RDiaz.  2011.  2-Deoxy-D-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease.. PLoS One. 6(7):e21788.

Zhao L, Mao Z, Schneider LS, Brinton RD.  2011.  Estrogen receptor β-selective phytoestrogenic formulation prevents physical and neurological changes in a preclinical model of human menopause.. Menopause. 18(10):1131-42.

Hanlon KE, Herman DS, Agnes RS, Largent-Milnes TM, Kumarasinghe IR, Ma SW, Guo W, Lee Y-S, Ossipov MH, Hruby VJ et al..  2011.  Novel peptide ligands with dual acting pharmacophores designed for the pathophysiology of neuropathic pain.. Brain Res. 1395:1-11.

Tarselli MA, Raehal KM, Brasher AK, Streicher JM, Groer CE, Cameron MD, Bohn LM, Micalizio GC.  2011.  Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain.. Nat Chem. 3(6):449-53.

Wang JMing, Singh C, Liu L, Irwin RW, Chen S, Chung EJi, Thompson RF, Brinton RDiaz.  2010.  Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease.. Proc Natl Acad Sci U S A. 107(14):6498-503.

Lozano-Ondoua AN, Wright C, Vardanyan A, King T, Largent-Milnes TM, Nelson M, Jimenez-Andrade JMiguel, Mantyh PW, Vanderah TW.  2010.  A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss.. Life Sci. 86(17-18):646-53.

Yao J, Hamilton RT, Cadenas E, Brinton RDiaz.  2010.  Decline in mitochondrial bioenergetics and shift to ketogenic profile in brain during reproductive senescence.. Biochim Biophys Acta. 1800(10):1121-6.

Streicher JM, Ren S, Herschman H, Wang Y.  2010.  MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart.. Circ Res. 106(8):1434-43.

Henderson VW, Brinton RDiaz.  2010.  Menopause and mitochondria: windows into estrogen effects on Alzheimer's disease risk and therapy.. Prog Brain Res. 182:77-96.

Largent-Milnes TM, Yamamoto T, Nair P, Moulton JW, Hruby VJ, Lai J, Porreca F, Vanderah TW.  2010.  Spinal or systemic TY005, a peptidic opioid agonist/neurokinin 1 antagonist, attenuates pain with reduced tolerance.. Br J Pharmacol. 161(5):986-1001.