Biblio

Ding F, Yao J, Zhao L, Mao Z, Chen S, Brinton RDiaz.  2013.  Ovariectomy induces a shift in fuel availability and metabolism in the hippocampus of the female transgenic model of familial Alzheimer's.. PLoS One. 8(3):e59825.

Yao J, Zhao L, Mao Z, Chen S, Wong KCarmen, To J, Brinton RDiaz.  2013.  Potentiation of brain mitochondrial function by S-equol and R/S-equol estrogen receptor β-selective phytoSERM treatments.. Brain Res. 1514:128-41.

Nair P, Yamamoto T, Largent-Milnes TM, Cowell S, Kulkarni V, Moye S, Navratilova E, Davis P, Ma S-W, Vanderah TW et al..  2013.  Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities.. Bioorg Med Chem Lett. 23(17):4975-8.

Jayaraman A, Carroll JC, Morgan TE, Lin S, Zhao L, Arimoto JM, M Murphy P, Beckett TL, Finch CE, Brinton RDiaz et al..  2012.  17β-estradiol and progesterone regulate expression of β-amyloid clearance factors in primary neuron cultures and female rat brain.. Endocrinology. 153(11):5467-79.

Roesly HB, Khan MR, Chen HDau Rw, Hill KA, Narendran N, Watts GS, Chen X, Dvorak K.  2012.  The decreased expression of Beclin-1 correlates with progression to esophageal adenocarcinoma: the role of deoxycholic acid.. Am J Physiol Gastrointest Liver Physiol. 302(8):G864-72.

Bali N, Arimoto JM, Iwata N, Lin SW, Zhao L, Brinton RD, Morgan TE, Finch CE.  2012.  Differential responses of progesterone receptor membrane component-1 (Pgrmc1) and the classical progesterone receptor (Pgr) to 17β-estradiol and progesterone in hippocampal subregions that support synaptic remodeling and neurogenesis.. Endocrinology. 153(2):759-69.

Wang JMing, Hou X, Adeosun S, Hill R, Henry S, Paul I, Irwin RW, Ou X-M, Bigler S, Stockmeier C et al..  2012.  A dominant negative ERβ splice variant determines the effectiveness of early or late estrogen therapy after ovariectomy in rats.. PLoS One. 7(3):e33493.

Yao J, Brinton RDiaz.  2012.  Estrogen regulation of mitochondrial bioenergetics: implications for prevention of Alzheimer's disease.. Adv Pharmacol. 64:327-71.

Lochhead JJ, Thorne RG.  2012.  Intranasal delivery of biologics to the central nervous system.. Adv Drug Deliv Rev. 64(7):614-28.

De Felice M, Melchiorri P, Ossipov MH, Vanderah TW, Porreca F, Negri L.  2012.  Mechanisms of Bv8-induced biphasic hyperalgesia: increased excitatory transmitter release and expression.. Neurosci Lett. 521(1):40-5.

Brinton RDiaz.  2012.  Minireview: translational animal models of human menopause: challenges and emerging opportunities.. Endocrinology. 153(8):3571-8.

Yao J, Irwin R, Chen S, Hamilton R, Cadenas E, Brinton RDiaz.  2012.  Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid.. Neurobiol Aging. 33(8):1507-21.

Tumati S, Largent-Milnes TM, Keresztes A, Ren J, Roeske WR, Vanderah TW, Varga EV.  2012.  Repeated morphine treatment-mediated hyperalgesia, allodynia and spinal glial activation are blocked by co-administration of a selective cannabinoid receptor type-2 agonist.. J Neuroimmunol. 244(1-2):23-31.

Irwin RW, Yao J, To J, Hamilton RT, Cadenas E, Brinton RD.  2012.  Selective oestrogen receptor modulators differentially potentiate brain mitochondrial function.. J Neuroendocrinol. 24(1):236-48.

Pajouhesh H, Feng Z-P, Zhang L, Pajouhesh H, Jiang X, Hendricson A, Dong H, Tringham E, Ding Y, Vanderah TW et al..  2012.  Structure-activity relationships of trimethoxybenzyl piperazine N-type calcium channel inhibitors.. Bioorg Med Chem Lett. 22(12):4153-8.

Tumati S, Largent-Milnes TM, Keresztes AI, Yamamoto T, Vanderah TW, Roeske WR, Hruby VJ, Varga EV.  2012.  Tachykinin NK₁ receptor antagonist co-administration attenuates opioid withdrawal-mediated spinal microglia and astrocyte activation.. Eur J Pharmacol. 684(1-3):64-70.

Lochhead JJ, McCaffrey G, Sanchez-Covarrubias L, Finch JD, DeMarco KM, Quigley CE, Davis TP, Ronaldson PT.  2012.  Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain.. Am J Physiol Heart Circ Physiol. 302(3):H582-93.

Zhao L, Yao J, Mao Z, Chen S, Wang Y, Brinton RDiaz.  2011.  17β-Estradiol regulates insulin-degrading enzyme expression via an ERβ/PI3-K pathway in hippocampus: relevance to Alzheimer's prevention.. Neurobiol Aging. 32(11):1949-63.

Yao J, Chen S, Mao Z, Cadenas E, Brinton RDiaz.  2011.  2-Deoxy-D-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease.. PLoS One. 6(7):e21788.

Lee YSun, Kulkarani V, Cowell SM, Ma S-W, Davis P, Hanlon KE, Vanderah TW, Lai J, Porreca F, Vardanyan R et al..  2011.  Development of potent μ and δ opioid agonists with high lipophilicity.. J Med Chem. 54(1):382-6.

Yamamoto T, Nair P, Largent-Milnes TM, Jacobsen NE, Davis P, Ma S-W, Yamamura HI, Vanderah TW, Porreca F, Lai J et al..  2011.  Discovery of a potent and efficacious peptide derivative for δ/μ opioid agonist/neurokinin 1 antagonist activity with a 2',6'-dimethyl-L-tyrosine: in vitro, in vivo, and NMR-based structural studies.. J Med Chem. 54(7):2029-38.

Rettberg JR, Hamilton RT, Mao Z, To J, Zhao L, Appt SE, Register TC, Kaplan JR, Brinton RDiaz.  2011.  The effect of dietary soy isoflavones before and after ovariectomy on hippocampal protein markers of mitochondrial bioenergetics and antioxidant activity in female monkeys.. Brain Res. 1379:23-33.

Yao J, Chen S, Cadenas E, Brinton RDiaz.  2011.  Estrogen protection against mitochondrial toxin-induced cell death in hippocampal neurons: antagonism by progesterone.. Brain Res. 1379:2-10.

Zhao L, Mao Z, Schneider LS, Brinton RD.  2011.  Estrogen receptor β-selective phytoestrogenic formulation prevents physical and neurological changes in a preclinical model of human menopause.. Menopause. 18(10):1131-42.

Hamilton RT, Rettberg JR, Mao Z, To J, Zhao L, Appt SE, Register TC, Kaplan JR, Brinton RDiaz.  2011.  Hippocampal responsiveness to 17β-estradiol and equol after long-term ovariectomy: implication for a therapeutic window of opportunity.. Brain Res. 1379:11-22.