Biblio

Nilles KL, Williams EI, Betterton RD, Davis TP, Ronaldson PT.  2022.  Blood-Brain Barrier Transporters: Opportunities for Therapeutic Development in Ischemic Stroke.. Int J Mol Sci. 23(3)

Betterton RD, Abdullahi W, Williams EI, Lochhead JJ, Brzica H, Stanton J, Reddell E, Ogbonnaya C, Davis TP, Ronaldson PT.  2022.  Regulation of Blood-Brain Barrier Transporters by Transforming Growth Factor-/Activin Receptor-Like Kinase 1 Signaling: Relevance to the Brain Disposition of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors (i.e., Statins).. Drug Metab Dispos. 50(7):942-956.

Stanton JA, Williams EI, Betterton RD, Davis TP, Ronaldson PT.  2022.  Targeting organic cation transporters at the blood-brain barrier to treat ischemic stroke in rats.. Exp Neurol. 357:114181.

Liktor-Busa E, Blawn KT, Kellohen KL, Wiese BM, Verkhovsky V, Wahl J, Vivek A, Palomino SM, Davis TP, Vanderah TW et al..  2020.  Functional NHE1 expression is critical to blood brain barrier integrity and sumatriptan blood to brain uptake.. PLoS One. 15(5):e0227463.

Ronaldson PT, Davis TP.  2020.  Regulation of blood-brain barrier integrity by microglia in health and disease: A therapeutic opportunity.. J Cereb Blood Flow Metab. 40(1_suppl):S6-S24.

Abdullahi W, Tripathi D, Ronaldson PT.  2018.  Blood-brain barrier dysfunction in ischemic stroke: targeting tight junctions and transporters for vascular protection.. Am J Physiol Cell Physiol. 315(3):C343-C356.

Cottier KE, Galloway EA, Calabrese EC, Tome ME, Liktor-Busa E, Kim J, Davis TP, Vanderah TW, Largent-Milnes TM.  2018.  Loss of Blood-Brain Barrier Integrity in a KCl-Induced Model of Episodic Headache Enhances CNS Drug Delivery.. eNeuro. 5(4)

Abdullahi W, Brzica H, Ibbotson K, Davis TP, Ronaldson PT.  2017.  Bone morphogenetic protein-9 increases the functional expression of organic anion transporting polypeptide 1a4 at the blood-brain barrier via the activin receptor-like kinase-1 receptor.. J Cereb Blood Flow Metab. 37(7):2340-2345.

Ibbotson K, Yell J, Ronaldson PT.  2017.  Nrf2 signaling increases expression of ATP-binding cassette subfamily C mRNA transcripts at the blood-brain barrier following hypoxia-reoxygenation stress.. Fluids Barriers CNS. 14(1):6.

Ronaldson PT, Bauer B, El-Kattan AF, Shen H, Salphati L, Louie SW.  2016.  Highlights From the AM Assoc of Pharmaceutical Scientists/International Transporter Consortium Joint Workshop on Drug Transporters in Absorption, Distribution, Metabolism, and Excretion: From the Bench to the Bedside - Clinical Pharmacology Considerations. Clin Pharmacol Ther. 100(5):419-422.

Lochhead JJ, Wolak DJ, Pizzo ME, Thorne RG.  2015.  Rapid transport within cerebral perivascular spaces underlies widespread tracer distribution in the brain after intranasal administration.. J Cereb Blood Flow Metab. 35(3):371-81.

Ronaldson PT, Davis TP.  2015.  Targeting transporters: promoting blood-brain barrier repair in response to oxidative stress injury.. Brain Res. 1623:39-52.

Thompson BJ, Sanchez-Covarrubias L, Slosky LM, Zhang Y, Laracuente M-L, Ronaldson PT.  2014.  Hypoxia/reoxygenation stress signals an increase in organic anion transporting polypeptide 1a4 (Oatp1a4) at the blood-brain barrier: relevance to CNS drug delivery.. J Cereb Blood Flow Metab. 34(4):699-707.

Ding F, Yao J, Rettberg JR, Chen S, Brinton RDiaz.  2013.  Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.. PLoS One. 8(11):e79977.

Lochhead JJ, Thorne RG.  2012.  Intranasal delivery of biologics to the central nervous system.. Adv Drug Deliv Rev. 64(7):614-28.

Lochhead JJ, McCaffrey G, Sanchez-Covarrubias L, Finch JD, DeMarco KM, Quigley CE, Davis TP, Ronaldson PT.  2012.  Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain.. Am J Physiol Heart Circ Physiol. 302(3):H582-93.

Lochhead JJ, McCaffrey G, Quigley CE, Finch J, DeMarco KM, Nametz N, Davis TP.  2010.  Oxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation.. J Cereb Blood Flow Metab. 30(9):1625-36.

McCaffrey G, Willis CL, Staatz WD, Nametz N, Quigley CA, Hom S, Lochhead JJ, Davis TP.  2009.  Occludin oligomeric assemblies at tight junctions of the blood-brain barrier are altered by hypoxia and reoxygenation stress.. J Neurochem. 110(1):58-71.