Biblio

Zhou L, Lovell KM, Frankowski KJ, Slauson SR, Phillips AM, Streicher JM, Stahl E, Schmid CL, Hodder P, Madoux F et al..  2013.  Development of functionally selective, small molecule agonists at kappa opioid receptors.. J Biol Chem. 288(51):36703-16.

Lozano-Ondoua AN, Hanlon KE, Symons-Liguori AM, Largent-Milnes TM, Havelin JJ, Ferland HL, Chandramouli A, Owusu-Ankomah M, Nikolich-Zugich T, Bloom AP et al..  2013.  Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists.. J Bone Miner Res. 28(1):92-107.

Ding F, Yao J, Rettberg JR, Chen S, Brinton RDiaz.  2013.  Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.. PLoS One. 8(11):e79977.

Zhao L, Mao Z, Chen S, Schneider LS, Brinton RD.  2013.  Early intervention with an estrogen receptor β-selective phytoestrogenic formulation prolongs survival, improves spatial recognition memory, and slows progression of amyloid pathology in a female mouse model of Alzheimer's disease.. J Alzheimers Dis. 37(2):403-19.

Petrov RR, Lee YSun, Vardanyan RS, Liu L, Ma S-W, Davis P, Lai J, Porreca F, Vanderah TW, Hruby VJ.  2013.  Effect of anchoring 4-anilidopiperidines to opioid peptides.. Bioorg Med Chem Lett. 23(11):3434-7.

Fuente-Martin E, Garcia-Caceres C, Morselli E, Clegg DJ, Chowen JA, Finan B, Brinton RD, Tschöp MH.  2013.  Estrogen, astrocytes and the neuroendocrine control of metabolism.. Rev Endocr Metab Disord. 14(4):331-8.

Schmid CL, Streicher JM, Groer CE, Munro TA, Zhou L, Bohn LM.  2013.  Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at κ-opioid receptors in striatal neurons.. J Biol Chem. 288(31):22387-98.

Jiang T, Yin F, Yao J, Brinton RD, Cadenas E.  2013.  Lipoic acid restores age-associated impairment of brain energy metabolism through the modulation of Akt/JNK signaling and PGC1α transcriptional pathway.. Aging Cell. 12(6):1021-31.

Cyr AR, Brown KE, McCormick ML, Coleman MC, Case AJ, Watts GS, Futscher BW, Spitz DR, Domann FE.  2013.  Maintenance of mitochondrial genomic integrity in the absence of manganese superoxide dismutase in mouse liver hepatocytes.. Redox Biol. 1:172-7.

Brinton RD.  2013.  Neurosteroids as regenerative agents in the brain: therapeutic implications.. Nat Rev Endocrinol. 9(4):241-50.

Podolsky AT, Sandweiss A, Hu J, Bilsky EJ, Cain JP, Kumirov VK, Lee YSun, Hruby VJ, Vardanyan RS, Vanderah TW.  2013.  Novel fentanyl-based dual μ/δ-opioid agonists for the treatment of acute and chronic pain.. Life Sci. 93(25-26):1010-6.

Ding F, Yao J, Zhao L, Mao Z, Chen S, Brinton RDiaz.  2013.  Ovariectomy induces a shift in fuel availability and metabolism in the hippocampus of the female transgenic model of familial Alzheimer's.. PLoS One. 8(3):e59825.

Yao J, Zhao L, Mao Z, Chen S, Wong KCarmen, To J, Brinton RDiaz.  2013.  Potentiation of brain mitochondrial function by S-equol and R/S-equol estrogen receptor β-selective phytoSERM treatments.. Brain Res. 1514:128-41.

Nair P, Yamamoto T, Largent-Milnes TM, Cowell S, Kulkarni V, Moye S, Navratilova E, Davis P, Ma S-W, Vanderah TW et al..  2013.  Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities.. Bioorg Med Chem Lett. 23(17):4975-8.

Singh M, Simpkins JW, Simpkins JW, Bimonte-Nelson HA, Bimonte-Nelson HA, Brinton RDiaz.  2013.  Window of opportunity for estrogen and progestin intervention in brain aging and Alzheimer's disease.. Brain Res. 1514:1-2.

Jayaraman A, Carroll JC, Morgan TE, Lin S, Zhao L, Arimoto JM, M Murphy P, Beckett TL, Finch CE, Brinton RDiaz et al..  2012.  17β-estradiol and progesterone regulate expression of β-amyloid clearance factors in primary neuron cultures and female rat brain.. Endocrinology. 153(11):5467-79.

Roesly HB, Khan MR, Chen HDau Rw, Hill KA, Narendran N, Watts GS, Chen X, Dvorak K.  2012.  The decreased expression of Beclin-1 correlates with progression to esophageal adenocarcinoma: the role of deoxycholic acid.. Am J Physiol Gastrointest Liver Physiol. 302(8):G864-72.

Bali N, Arimoto JM, Iwata N, Lin SW, Zhao L, Brinton RD, Morgan TE, Finch CE.  2012.  Differential responses of progesterone receptor membrane component-1 (Pgrmc1) and the classical progesterone receptor (Pgr) to 17β-estradiol and progesterone in hippocampal subregions that support synaptic remodeling and neurogenesis.. Endocrinology. 153(2):759-69.

Béguin C, Potuzak J, Xu W, Liu-Chen L-Y, Streicher JM, Groer CE, Bohn LM, Carlezon WA, Cohen BM.  2012.  Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues.. Bioorg Med Chem Lett. 22(2):1023-6.

Frankowski KJ, Hedrick MP, Gosalia P, Li K, Shi S, Whipple D, Ghosh P, Prisinzano TE, Schoenen FJ, Su Y et al..  2012.  Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy.. ACS Chem Neurosci. 3(3):221-236.

Wang JMing, Hou X, Adeosun S, Hill R, Henry S, Paul I, Irwin RW, Ou X-M, Bigler S, Stockmeier C et al..  2012.  A dominant negative ERβ splice variant determines the effectiveness of early or late estrogen therapy after ovariectomy in rats.. PLoS One. 7(3):e33493.

Yao J, Brinton RDiaz.  2012.  Estrogen regulation of mitochondrial bioenergetics: implications for prevention of Alzheimer's disease.. Adv Pharmacol. 64:327-71.

Lochhead JJ, Thorne RG.  2012.  Intranasal delivery of biologics to the central nervous system.. Adv Drug Deliv Rev. 64(7):614-28.

Jandova J, Beyer TE, Meuillet EJ, Watts GS.  2012.  The matrix protein CCN1/CYR61 is required for α(V)β5-mediated cancer cell migration.. Cell Biochem Funct. 30(8):687-95.

De Felice M, Melchiorri P, Ossipov MH, Vanderah TW, Porreca F, Negri L.  2012.  Mechanisms of Bv8-induced biphasic hyperalgesia: increased excitatory transmitter release and expression.. Neurosci Lett. 521(1):40-5.