2012
Wang, Jun Ming, et al. “A Dominant Negative ERβ Splice Variant Determines the Effectiveness of Early or Late Estrogen Therapy After Ovariectomy in Rats.”. PLoS One, vol. 7, no. 3, Jan. 2012, p. e33493, https://doi.org/10.1371/journal.pone.0033493.
Béguin, Cécile, et al. “Differential Signaling Properties at the Kappa Opioid Receptor of 12-Epi-Salvinorin A and Its Analogues.”. Bioorg Med Chem Lett, vol. 22, no. 2, Jan. 2012, pp. 1023-6, https://doi.org/10.1016/j.bmcl.2011.11.128.
Frankowski, Kevin J, et al. “Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy.”. ACS Chem Neurosci, vol. 3, no. 3, Jan. 2012, pp. 221-36, https://doi.org/10.1021/cn200128x.
Yao, Jia, and Brinton, Roberta Diaz. “Estrogen Regulation of Mitochondrial Bioenergetics: Implications for Prevention of Alzheimer’s Disease.”. Adv Pharmacol, vol. 64, Jan. 2012, pp. 327-71, https://doi.org/10.1016/B978-0-12-394816-8.00010-6.
Lochhead, Jeffrey J, and Thorne, Robert G. “Intranasal Delivery of Biologics to the Central Nervous System.”. Adv Drug Deliv Rev, vol. 64, no. 7, Jan. 2012, pp. 614-28, https://doi.org/10.1016/j.addr.2011.11.002.
De Felice, Milena, et al. “Mechanisms of Bv8-Induced Biphasic Hyperalgesia: Increased Excitatory Transmitter Release and Expression.”. Neurosci Lett, vol. 521, no. 1, Jan. 2012, pp. 40-5, https://doi.org/10.1016/j.neulet.2012.05.055.
Irwin, R W, et al. “Selective Oestrogen Receptor Modulators Differentially Potentiate Brain Mitochondrial Function.”. J Neuroendocrinol, vol. 24, no. 1, Jan. 2012, pp. 236-48, https://doi.org/10.1111/j.1365-2826.2011.02251.x.
Pajouhesh, Hassan, et al. “Structure-Activity Relationships of Trimethoxybenzyl Piperazine N-Type Calcium Channel Inhibitors.”. Bioorg Med Chem Lett, vol. 22, no. 12, Jan. 2012, pp. 4153-8, https://doi.org/10.1016/j.bmcl.2012.04.054.
Tumati, Suneeta, et al. “Tachykinin NK₁ Receptor Antagonist Co-Administration Attenuates Opioid Withdrawal-Mediated Spinal Microglia and Astrocyte Activation.”. Eur J Pharmacol, vol. 684, no. 1-3, Jan. 2012, pp. 64-70.
Lochhead, Jeffrey J, et al. “Tempol Modulates Changes in Xenobiotic Permeability and Occludin Oligomeric Assemblies at the Blood-Brain Barrier During Inflammatory Pain.”. Am J Physiol Heart Circ Physiol, vol. 302, no. 3, Jan. 2012, pp. H582-93, https://doi.org/10.1152/ajpheart.00889.2011.
Roesly, Heather B, et al. “The Decreased Expression of Beclin-1 Correlates With Progression to Esophageal Adenocarcinoma: The Role of Deoxycholic Acid.”. Am J Physiol Gastrointest Liver Physiol, vol. 302, no. 8, Jan. 2012, pp. G864-72, https://doi.org/10.1152/ajpgi.00340.2011.
2011
Zhao, Liqin, et al. “17β-Estradiol Regulates Insulin-Degrading Enzyme Expression via an ERβ PI3-K Pathway in Hippocampus: Relevance to Alzheimer’s Prevention.”. Neurobiol Aging, vol. 32, no. 11, Nov. 2011, pp. 1949-63, https://doi.org/10.1016/j.neurobiolaging.2009.12.010.
Zhao, Liqin, et al. “Estrogen Receptor β-Selective Phytoestrogenic Formulation Prevents Physical and Neurological Changes in a Preclinical Model of Human Menopause.”. Menopause, vol. 18, no. 10, Oct. 2011, pp. 1131-42, https://doi.org/10.1097/gme.0b013e3182175b66.
Yao, Jia, et al. “Shift in Brain Metabolism in Late Onset Alzheimer’s Disease: Implications for Biomarkers and Therapeutic Interventions.”. Mol Aspects Med, vol. 32, no. 4-6, Aug. 2011, pp. 247-57, https://doi.org/10.1016/j.mam.2011.10.005.
“The Role of Soy Isoflavones in Menopausal Health: Report of The North American Menopause Society Wulf H. Utian Translational Science Symposium in Chicago, IL (October 2010).”. “”. Menopause, vol. 18, no. 7, July 2011, pp. 732-53, https://doi.org/10.1097/gme.0b013e31821fc8e0.
Tarselli, Michael A, et al. “Synthesis of Conolidine, a Potent Non-Opioid Analgesic for Tonic and Persistent Pain.”. Nat Chem, vol. 3, no. 6, June 2011, pp. 449-53, https://doi.org/10.1038/nchem.1050.
Irwin, Ronald W, et al. “Medroxyprogesterone Acetate Antagonizes Estrogen Up-Regulation of Brain Mitochondrial Function.”. Endocrinology, vol. 152, no. 2, Feb. 2011, pp. 556-67, https://doi.org/10.1210/en.2010-1061.
Yao, Jia, et al. “2-Deoxy-D-Glucose Treatment Induces Ketogenesis, Sustains Mitochondrial Function, and Reduces Pathology in Female Mouse Model of Alzheimer’s Disease.”. PLoS One, vol. 6, no. 7, Jan. 2011, p. e21788, https://doi.org/10.1371/journal.pone.0021788.
Lee, Yeon Sun, et al. “Development of Potent μ and δ Opioid Agonists With High Lipophilicity.”. J Med Chem, vol. 54, no. 1, Jan. 2011, pp. 382-6, https://doi.org/10.1021/jm100982d.
Yamamoto, Takashi, et al. “Discovery of a Potent and Efficacious Peptide Derivative for δ μ Opioid Agonist Neurokinin 1 Antagonist Activity With a 2’,6’-Dimethyl-L-Tyrosine: In Vitro, in Vivo, and NMR-Based Structural Studies.”. J Med Chem, vol. 54, no. 7, Jan. 2011, pp. 2029-38, https://doi.org/10.1021/jm101023r.
Yao, Jia, et al. “Estrogen Protection Against Mitochondrial Toxin-Induced Cell Death in Hippocampal Neurons: Antagonism by Progesterone.”. Brain Res, vol. 1379, Jan. 2011, pp. 2-10, https://doi.org/10.1016/j.brainres.2010.11.090.
Hamilton, Ryan T, et al. “Hippocampal Responsiveness to 17β-Estradiol and Equol After Long-Term Ovariectomy: Implication for a Therapeutic Window of Opportunity.”. Brain Res, vol. 1379, Jan. 2011, pp. 11-22, https://doi.org/10.1016/j.brainres.2011.01.029.
Sukhtankar, Devki, et al. “Inhibition of P38-MAPK Signaling Pathway Attenuates Breast Cancer Induced Bone Pain and Disease Progression in a Murine Model of Cancer-Induced Bone Pain.”. Mol Pain, vol. 7, Jan. 2011, p. 81, https://doi.org/10.1186/1744-8069-7-81.
Tumati, S, et al. “Intrathecal PKA-Selective SiRNA Treatment Blocks Sustained Morphine-Mediated Pain Sensitization and Antinociceptive Tolerance in Rats.”. J Neurosci Methods, vol. 199, no. 1, Jan. 2011, pp. 62-8, https://doi.org/10.1016/j.jneumeth.2011.04.036.
Wu, Tzu-Wei, et al. “Membrane Estrogen Receptors Mediate Calcium Signaling and MAP Kinase Activation in Individual Hippocampal Neurons.”. Brain Res, vol. 1379, Jan. 2011, pp. 34-43, https://doi.org/10.1016/j.brainres.2011.01.034.