Patrick W Mantyh

Professor, Pharmacology

Contact Information

Office: 560
Building: Life Sciences North
Phone: (520) 626-0742

Email: pmantyh@email.arizona.edu

Research Area:

Cancer Pharmacology/Biology

Molecular and Biochemical Pharmacology

Neuroscience and Pain

Research Interests:

Cancer, cancer pain and non-malignant bone pain, stem cells and skeletal health in disease and aging.

Publications

2016

The cystine/glutamate antiporter system xc- drives breast tumor cell glutamate release and cancer-induced bone pain.

2015

Orthopedic surgery and bone fracture pain are both significantly attenuated by sustained blockade of nerve growth factor.

Spinal dopaminergic projections control the transition to pathological pain plasticity via a D1/D5-mediated mechanism.

2013

Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists.

2010

A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss.