Synthesis of ()()-Tiruchanduramine.

TitleSynthesis of ()()-Tiruchanduramine.
Publication TypeJournal Article
Year of Publication2022
AuthorsAl-Taie ZS, Bartholomew B, Cartmell C, Froom RT, Kerr RG, Kraehenbuehl R, Murphy PJ, Nash RJ, Penkova YB, van Teijlingen A
JournalMolecules
Volume27
Issue4
Date Published2022 Feb 16
ISSN1420-3049
KeywordsAlkaloids, Chemistry Techniques, Synthetic, Combinatorial Chemistry Techniques, Molecular Structure
Abstract

The absolute stereochemistry of the marine alkaloid ()-()-tiruchanduramine was established via a convergent total synthesis in six steps and 15.5% overall yield from Fmoc-D-Dab(Boc)-OH.

DOI10.3390/molecules27041338
Alternate JournalMolecules
PubMed ID35209136
PubMed Central IDPMC8880061
Grant ListNA / / Atlantic Canada Opportunities Agency /
NA / / Canada Foundation for Innovation /
NA / / Iraqi government /
NA / / European Regional Development Fund (ERDF) /
Faculty Member Reference: 
Christopher Cartmell