Biblio
Found 41 results
Filters: Author is Porreca, Frank [Clear All Filters]
Chronic pain recruits hypothalamic dynorphin/kappa opioid receptor signalling to promote wakefulness and vigilance.. Brain. 146(3):1186-1199.
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2023. Medication overuse headache.. Nat Rev Dis Primers. 9(1):5.
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2023. Conotoxin contulakin-G engages a neurotensin receptor 2/R-type calcium channel (Cav2.3) pathway to mediate spinal antinociception.. Pain. 163(9):1751-1762.
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2022. Cutaneous heat and light-induced pain thresholds in post-traumatic headache attributed to mild traumatic brain injury.. Headache. 62(6):726-736.
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2022. Dysregulation of serum prolactin links the hypothalamus with female nociceptors to promote migraine.. Brain. 145(8):2894-2909.
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2022. Editorial: Chronic orofacial pain.. Front Pain Res (Lausanne). 3:1086256.
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2022. Exploring the neurobiology of the premonitory phase of migraine preclinically - a role for hypothalamic kappa opioid receptors? J Headache Pain. 23(1):126.
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2022. Kappa Opioid Receptor Blockade in the Amygdala Mitigates Pain Like-Behaviors by Inhibiting Corticotropin Releasing Factor Neurons in a Rat Model of Functional Pain.. Front Pharmacol. 13:903978.
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2022. Preclinical assessment of onabotulinumtoxinA for the treatment of mild traumatic brain injury-related acute and persistent post-traumatic headache.. Cephalalgia. 42(11-12):1194-1206.
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2022. A prolactin-dependent sexually dimorphic mechanism of migraine chronification.. Cephalalgia. 42(3):197-208.
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2021.
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2019.
Kappa opioid receptor antagonists: A possible new class of therapeutics for migraine prevention.. Cephalalgia. 37(8):780-794.
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2017. Long-lasting antinociceptive effects of green light in acute and chronic pain in rats.. Pain. 158(2):347-360.
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2017. Recent Advances in the Realm of Allosteric Modulators for Opioid Receptors for Future Therapeutics.. ACS Chem Neurosci. 8(6):1147-1158.
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2017. Cyclic non-opioid dynorphin A analogues for the bradykinin receptors.. Bioorg Med Chem Lett. 26(22):5513-5516.
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2016. Discovery of Stable Non-opioid Dynorphin A Analogues Interacting at the Bradykinin Receptors for the Treatment of Neuropathic Pain.. ACS Chem Neurosci. 7(12):1746-1752.
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2016. .
2016. Structure-Activity Relationships of [des-Arg(7)]Dynorphin A Analogues at the κ Opioid Receptor.. J Med Chem. 59(22):10291-10298.
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2016. Various modifications of the amphipathic dynorphin A pharmacophore for rat brain bradykinin receptors.. Chem Biol Drug Des. 88(4):615-9.
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2016. Blockade of non-opioid excitatory effects of spinal dynorphin A at bradykinin receptors.. Receptors Clin Investig. 2(1)
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2015. Design and synthesis of novel bivalent ligands (MOR and DOR) by conjugation of enkephalin analogues with 4-anilidopiperidine derivatives.. Bioorg Med Chem Lett. 25(20):4683-8.
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2015. Discovery of 5-substituted tetrahydronaphthalen-2yl-methyl with N-phenyl-N-(piperidin-4-yl)propionamide derivatives as potent opioid receptor ligands.. Bioorg Med Chem. 23(18):6185-94.
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2015. Discovery of Novel Multifunctional Ligands with μ/δ Opioid Agonist/Neurokinin-1 (NK1) Antagonist Activities for the Treatment of Pain.. J Med Chem. 58(21):8573-83.
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2015. Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states.. Brain. 138(Pt 1):28-35.
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2015.