|Title||Medication overuse headache.|
|Publication Type||Journal Article|
|Year of Publication||2023|
|Authors||Ashina S, Terwindt GM, Steiner TJ, Lee MJi, Porreca F, Tassorelli C, Schwedt TJ, Jensen RH, Diener H-C, Lipton RB|
|Journal||Nat Rev Dis Primers|
|Date Published||2023 Feb 02|
|Keywords||Headache, Headache Disorders, Secondary, Humans, Migraine Disorders, Quality of Life|
Medication overuse headache (MOH) is a secondary headache disorder attributed to overuse of acute headache medications by a person with an underlying headache disorder, usually migraine or tension-type headache. MOH is common among individuals with 15 or more headache days per month. Although MOH is associated with substantial disability and reductions in quality of life, this condition is often under-recognized. As MOH is both preventable and treatable, it warrants greater attention and awareness. The diagnosis of MOH is based on the history and an unremarkable neurological examination, and is made according to the diagnostic criteria of the International Classification of Headache Disorders third edition (ICHD-3). Pathophysiological mechanisms of MOH include altered descending pain modulation, central sensitization and biobehavioural factors. Treatment of MOH includes the use of headache preventive therapies, but essential to success is eliminating the cause, by reducing the frequency of use of acute headache medication, and perhaps withdrawing the overused medication altogether. Appropriate treatment is usually highly effective, leading to reduced headache burden and acute medication consumption.
|Alternate Journal||Nat Rev Dis Primers|
Medication overuse headache.
Faculty Member Reference:
Frank Porreca, PhD