Found 89 results
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Zhang Y, Williams DA, Zaidi SA, Yuan Y, Braithwaite A, Bilsky EJ, Dewey WL, Akbarali HI, Streicher JM, Selley DE.  2016.  17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-(4'-pyridylcarboxamido)morphinan (NAP) Modulating the Mu Opioid Receptor in a Biased Fashion.. ACS Chem Neurosci. 7(3):297-304.
Jenkins LM, Singh P, Varadaraj A, Lee NY, Shah S, Flores HV, O'Connell K, Mythreye K.  2016.  Altering the Proteoglycan State of Transforming Growth Factor β Type III Receptor (TβRIII)/Betaglycan Modulates Canonical Wnt/β-Catenin Signaling.. J Biol Chem. 291(49):25716-25728.
Cowell SM, Lee YSun.  2016.  Biphalin: The Foundation of Bivalent Ligands.. Curr Med Chem. 23(29):3267-3284.
Remesic M, Lee YSun, Hruby VJ.  2016.  Cyclic Opioid Peptides.. Curr Med Chem. 23(13):1288-303.
Hall SM, Lee YSun, Hruby VJ.  2016.  Dynorphin A analogs for the treatment of chronic neuropathic pain.. Future Med Chem. 8(2):165-77.
Karim R, Dang H, Henderson VW, Hodis HN, St John J, Brinton RD, Mack WJ.  2016.  Effect of Reproductive History and Exogenous Hormone Use on Cognitive Function in Mid- and Late Life.. J Am Geriatr Soc. 64(12):2448-2456.
Deekonda S, Cole J, Sunna S, Rankin D, Largent-Milnes TM, Davis P, BassiriRad NM, Lai J, Vanderah TW, Porecca F et al..  2016.  Enkephalin analogues with N-phenyl-N-(piperidin-2-ylmethyl)propionamide derivatives: Synthesis and biological evaluations.. Bioorg Med Chem Lett. 26(1):222-7.
Ronaldson PT, Bauer B, El-Kattan AF, Shen H, Salphati L, Louie SW.  2016.  Highlights From the AM Assoc of Pharmaceutical Scientists/International Transporter Consortium Joint Workshop on Drug Transporters in Absorption, Distribution, Metabolism, and Excretion: From the Bench to the Bedside - Clinical Pharmacology Considerations. Clin Pharmacol Ther. 100(5):419-422.
Rettberg JR, Dang H, Hodis HN, Henderson VW, St John JA, Mack WJ, Brinton RDiaz.  2016.  Identifying postmenopausal women at risk for cognitive decline within a healthy cohort using a panel of clinical metabolic indicators: potential for detecting an at-Alzheimer's risk metabolic phenotype.. Neurobiol Aging. 40:155-63.
Zhao L, Mao Z, Woody SK, Brinton RD.  2016.  Sex differences in metabolic aging of the brain: insights into female susceptibility to Alzheimer's disease.. Neurobiol Aging. 42:69-79.
Karim R, Stanczyk FZ, Brinton RD, Rettberg J, Hodis HN, Mack WJ.  2015.  Association of endogenous sex hormones with adipokines and ghrelin in postmenopausal women.. J Clin Endocrinol Metab. 100(2):508-15.
Moutal A, Honnorat J, Massoma P, Désormeaux P, Bertrand C, Malleval C, Watrin C, Chounlamountri N, Mayeur M-E, Besançon R et al..  2015.  CRMP5 Controls Glioblastoma Cell Proliferation and Survival through Notch-Dependent Signaling.. Cancer Res. 75(17):3519-28.
Munawar MA, Lee YSun, Rankin D, Munir J, Lai J, Khan MA, Hruby VJ.  2015.  Design, synthesis, and biological evaluation of a series of bifunctional ligands of opioids/SSRIs.. Bioorg Med Chem. 23(6):1251-9.
Giri AKumar, Apostol CR, Wang Y, Forte BL, Largent-Milnes TM, Davis P, Rankin D, Molnar G, Olson KM, Porreca F et al..  2015.  Discovery of Novel Multifunctional Ligands with μ/δ Opioid Agonist/Neurokinin-1 (NK1) Antagonist Activities for the Treatment of Pain.. J Med Chem. 58(21):8573-83.
Varadaraj A, Patel P, Serrao A, Bandyopadhay T, Lee NY, Jazaeri AA, Huang Z, Murphy SK, Mythreye K.  2015.  Epigenetic Regulation of GDF2 Suppresses Anoikis in Ovarian and Breast Epithelia.. Neoplasia. 17(11):826-38.
Samulitis BK, Pond KW, Pond E, Cress AE, Patel H, Wisner L, Patel C, Dorr RT, Landowski TH.  2015.  Gemcitabine resistant pancreatic cancer cell lines acquire an invasive phenotype with collateral hypersensitivity to histone deacetylase inhibitors.. Cancer Biol Ther. 16(1):43-51.
Espeland MA, Brinton RDiaz, Hugenschmidt C, Manson JAE, Craft S, Yaffe K, Weitlauf J, Vaughan L, Johnson KC, Padula CB et al..  2015.  Impact of Type 2 Diabetes and Postmenopausal Hormone Therapy on Incidence of Cognitive Impairment in Older Women.. Diabetes Care. 38(12):2316-24.
Brinton RD, Yao J, Yin F, Mack WJ, Cadenas E.  2015.  Perimenopause as a neurological transition state.. Nat Rev Endocrinol. 11(7):393-405.
Espeland MA, Brinton RDiaz, Manson JAE, Yaffe K, Hugenschmidt C, Vaughan L, Craft S, Edwards BJ, Casanova R, Masaki K et al..  2015.  Postmenopausal hormone therapy, type 2 diabetes mellitus, and brain volumes.. Neurology. 85(13):1131-8.
Frankowski KJ, Slauson SR, Lovell KM, Phillips AM, Streicher JM, Zhou L, Whipple DA, Schoenen FJ, Prisinzano TE, Bohn LM et al..  2015.  Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif.. Bioorg Med Chem. 23(14):3948-56.
Caldwell CC, Yao J, Brinton RDiaz.  2015.  Targeting the prodromal stage of Alzheimer's disease: bioenergetic and mitochondrial opportunities.. Neurotherapeutics. 12(1):66-80.
Ronaldson PT, Davis TP.  2015.  Targeting transporters: promoting blood-brain barrier repair in response to oxidative stress injury.. Brain Res. 1623:39-52.