Publications

Year of Publicationsort descending Title Faculty Association
2011 Estrogen receptor β-selective phytoestrogenic formulation prevents physical and neurological changes in a preclinical model of human menopause. Roberta Diaz Brinton, Ph.D
2011 Synthesis and biological evaluation of new opioid agonist and neurokinin-1 antagonist bivalent ligands. Victor Hruby, Ph.D., Josephine Lai , Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD, Eva Varga, Ph.D.
2011 Estrogen protection against mitochondrial toxin-induced cell death in hippocampal neurons: antagonism by progesterone. Roberta Diaz Brinton, Ph.D
2011 Medroxyprogesterone acetate antagonizes estrogen up-regulation of brain mitochondrial function. Roberta Diaz Brinton, Ph.D
2011 Targeting mitochondrial bioenergetics for Alzheimer's prevention and treatment. Roberta Diaz Brinton, Ph.D
2011 Discovery of a potent and efficacious peptide derivative for δ/μ opioid agonist/neurokinin 1 antagonist activity with a 2',6'-dimethyl-L-tyrosine: in vitro, in vivo, and NMR-based structural studies. Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD
2011 Inhibition of p38-MAPK signaling pathway attenuates breast cancer induced bone pain and disease progression in a murine model of cancer-induced bone pain. Frank Porreca, PhD, Todd Vanderah, PhD
2012 Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice. Roberta Diaz Brinton, Ph.D
2012 Continuous versus cyclic progesterone exposure differentially regulates hippocampal gene expression and functional profiles. Roberta Diaz Brinton, Ph.D
2012 Activation of TRPA1 on dural afferents: a potential mechanism of headache pain. Frank Porreca, PhD, Todd Vanderah, PhD
2012 Activation of descending pain-facilitatory pathways from the rostral ventromedial medulla by cholecystokinin elicits release of prostaglandin-E₂ in the spinal cord. Josephine Lai , Ph.D., Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD
2012 Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid. Roberta Diaz Brinton, Ph.D
2012 A dominant negative ERβ splice variant determines the effectiveness of early or late estrogen therapy after ovariectomy in rats. Roberta Diaz Brinton, Ph.D
2012 Repeated morphine treatment-mediated hyperalgesia, allodynia and spinal glial activation are blocked by co-administration of a selective cannabinoid receptor type-2 agonist. Tally Largent-Milnes, PhD, William R. Roeske, MD, Todd Vanderah, PhD, Eva Varga, Ph.D.
2012 17β-estradiol and progesterone regulate expression of β-amyloid clearance factors in primary neuron cultures and female rat brain. Roberta Diaz Brinton, Ph.D
2012 Allopregnanolone increases the number of dopaminergic neurons in substantia nigra of a triple transgenic mouse model of Alzheimer's disease. Roberta Diaz Brinton, Ph.D
2012 The decreased expression of Beclin-1 correlates with progression to esophageal adenocarcinoma: the role of deoxycholic acid. George Watts, Ph.D.
2012 Intranasal delivery of biologics to the central nervous system. Jeffrey J. Lochhead, PhD
2012 Estrogen regulation of mitochondrial bioenergetics: implications for prevention of Alzheimer's disease. Roberta Diaz Brinton, Ph.D
2012 Structure-activity relationships of trimethoxybenzyl piperazine N-type calcium channel inhibitors. Frank Porreca, PhD, Todd Vanderah, PhD
2012 Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues. John M. Streicher, PhD
2012 Allopregnanolone reinstates tyrosine hydroxylase immunoreactive neurons and motor performance in an MPTP-lesioned mouse model of Parkinson's disease. Roberta Diaz Brinton, Ph.D
2012 Considerations in the design of clinical trials for cognitive aging. Roberta Diaz Brinton, Ph.D
2012 The matrix protein CCN1/CYR61 is required for α(V)β5-mediated cancer cell migration. George Watts, Ph.D.
2012 Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain. Thomas P Davis, PhD, Jeffrey J. Lochhead, PhD, Patrick T Ronaldson, PhD

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