Publications

Year of Publicationsort descending Title Faculty Association
2012 Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice. Roberta Diaz Brinton, Ph.D
2012 Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy. John M. Streicher, PhD
2012 Continuous versus cyclic progesterone exposure differentially regulates hippocampal gene expression and functional profiles. Roberta Diaz Brinton, Ph.D
2012 Activation of TRPA1 on dural afferents: a potential mechanism of headache pain. Frank Porreca, PhD, Todd Vanderah, PhD
2012 Activation of descending pain-facilitatory pathways from the rostral ventromedial medulla by cholecystokinin elicits release of prostaglandin-E₂ in the spinal cord. Josephine Lai , Ph.D., Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD
2012 Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid. Roberta Diaz Brinton, Ph.D
2013 Cancer-induced bone pain: Mechanisms and models. Todd Vanderah, PhD
2013 Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists. Patrick W Mantyh, Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD
2013 Potentiation of brain mitochondrial function by S-equol and R/S-equol estrogen receptor β-selective phytoSERM treatments. Roberta Diaz Brinton, Ph.D
2013 Age-dependent modulation of synaptic plasticity and insulin mimetic effect of lipoic acid on a mouse model of Alzheimer's disease. Roberta Diaz Brinton, Ph.D, Fei Yin, Ph.D.
2013 Novel fentanyl-based dual μ/δ-opioid agonists for the treatment of acute and chronic pain. Victor Hruby, Ph.D., Yeon Sun Lee, Todd Vanderah, PhD
2013 Development of functionally selective, small molecule agonists at kappa opioid receptors. John M. Streicher, PhD
2013 Effect of anchoring 4-anilidopiperidines to opioid peptides. Victor Hruby, Ph.D., Josephine Lai , Ph.D., Yeon Sun Lee, Frank Porreca, PhD, Todd Vanderah, PhD
2013 Window of opportunity for estrogen and progestin intervention in brain aging and Alzheimer's disease. Roberta Diaz Brinton, Ph.D
2013 Building a better analgesic: multifunctional compounds that address injury-induced pathology to enhance analgesic efficacy while eliminating unwanted side effects. Victor Hruby, Ph.D., Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD
2013 Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention. Roberta Diaz Brinton, Ph.D
2013 Early intervention with an estrogen receptor β-selective phytoestrogenic formulation prolongs survival, improves spatial recognition memory, and slows progression of amyloid pathology in a female mouse model of Alzheimer's disease. Roberta Diaz Brinton, Ph.D
2013 Chiral Effect of a Phe Residue in Position 3 of the Dmt(1)-L(or D)-Tic(2) Analogues on Opioid Functional Activities. Yeon Sun Lee, Frank Porreca, PhD
2013 Maintenance of mitochondrial genomic integrity in the absence of manganese superoxide dismutase in mouse liver hepatocytes. George Watts, Ph.D.
2013 Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities. Victor Hruby, Ph.D., Josephine Lai , Ph.D., Tally Largent-Milnes, PhD, Edita Navratilova, Frank Porreca, PhD, Todd Vanderah, PhD
2013 Estrogen, astrocytes and the neuroendocrine control of metabolism. Roberta Diaz Brinton, Ph.D
2013 Ovariectomy induces a shift in fuel availability and metabolism in the hippocampus of the female transgenic model of familial Alzheimer's. Roberta Diaz Brinton, Ph.D
2013 Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism. Thomas P Davis, PhD, Patrick T Ronaldson, PhD, Todd Vanderah, PhD
2013 Lipoic acid restores age-associated impairment of brain energy metabolism through the modulation of Akt/JNK signaling and PGC1α transcriptional pathway. Roberta Diaz Brinton, Ph.D
2013 Neurosteroids as regenerative agents in the brain: therapeutic implications. Roberta Diaz Brinton, Ph.D

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