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2013 |
Building a better analgesic: multifunctional compounds that address injury-induced pathology to enhance analgesic efficacy while eliminating unwanted side effects. |
Peg Davis, Victor Hruby, Ph.D., Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD |
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2013 |
Development of functionally selective, small molecule agonists at kappa opioid receptors. |
John M. Streicher, PhD |
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2013 |
Window of opportunity for estrogen and progestin intervention in brain aging and Alzheimer's disease. |
Roberta Diaz Brinton, Ph.D |
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2013 |
Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities. |
Victor Hruby, Ph.D., Josephine Lai , Ph.D., Tally Largent-Milnes, PhD, Edita Navratilova, Frank Porreca, PhD, Todd Vanderah, PhD |
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2014 |
Reversal of metabolic deficits by lipoic acid in a triple transgenic mouse model of Alzheimer's disease: a 13C NMR study. |
Roberta Diaz Brinton, Ph.D |
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2014 |
Intranasal drug delivery to the brain |
Jeffrey J. Lochhead, PhD |
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2014 |
Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling. |
Nam Lee, Ph.D. |
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2014 |
Hypoxia/reoxygenation stress signals an increase in organic anion transporting polypeptide 1a4 (Oatp1a4) at the blood-brain barrier: relevance to CNS drug delivery. |
Patrick T Ronaldson, PhD, FAAPS |
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2014 |
Environmental arsenic exposure and microbiota in induced sputum. |
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2014 |
The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth. |
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2014 |
Hypermetabolic state in the 7-month-old triple transgenic mouse model of Alzheimer's disease and the effect of lipoic acid: a 13C-NMR study. |
Roberta Diaz Brinton, Ph.D |
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2014 |
Src-mediated post-translational regulation of endoglin stability and function is critical for angiogenesis. |
Nam Lee, Ph.D. |
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2014 |
Neuropathic plasticity in the opioid and non-opioid actions of dynorphin A fragments and their interactions with bradykinin B2 receptors on neuronal activity in the rat spinal cord. |
Frank Porreca, PhD |
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2014 |
Three-dimensional printing surgical instruments: are we there yet? |
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2014 |
Physiological temperatures drive glutamate release onto trigeminal superficial dorsal horn neurons. |
Tally Largent-Milnes, PhD |
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2014 |
Differential neuroprotective potential of CRMP2 peptide aptamers conjugated to cationic, hydrophobic, and amphipathic cell penetrating peptides. |
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2014 |
Structure-activity relationships of non-opioid [des-Arg(7)]-dynorphin A analogues for bradykinin receptors. |
Frank Porreca, PhD |
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2014 |
Capsaicin-responsive corneal afferents do not contain TRPV1 at their central terminals in trigeminal nucleus caudalis in rats. |
Tally Largent-Milnes, PhD |
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2014 |
Discovery of amphipathic dynorphin A analogues to inhibit the neuroexcitatory effects of dynorphin A through bradykinin receptors in the spinal cord. |
Victor Hruby, Ph.D., Josephine Lai , Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD |
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2014 |
Synthesis and evaluation of bivalent ligands for binding to the human melanocortin-4 receptor. |
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2014 |
Frontiers in therapeutic development of allopregnanolone for Alzheimer's disease and other neurological disorders. |
Roberta Diaz Brinton, Ph.D |
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2014 |
External QX-314 inhibits evoked cranial primary afferent synaptic transmission independent of TRPV1. |
Tally Largent-Milnes, PhD |
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2014 |
Animal models for opioid addiction drug discovery. |
Tally Largent-Milnes, PhD, Todd Vanderah, PhD |
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2014 |
Behavioral and cellular pharmacology characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan (NAQ) as a mu opioid receptor selective ligand. |
John M. Streicher, PhD |
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2014 |
Estrogen: a master regulator of bioenergetic systems in the brain and body. |
Roberta Diaz Brinton, Ph.D |
