Found 96 results
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Samulitis BK, Pond KW, Pond E, Cress AE, Patel H, Wisner L, Patel C, Dorr RT, Landowski TH.  2015.  Gemcitabine resistant pancreatic cancer cell lines acquire an invasive phenotype with collateral hypersensitivity to histone deacetylase inhibitors.. Cancer Biol Ther. 16(1):43-51.
Espeland MA, Brinton RDiaz, Hugenschmidt C, Manson JAE, Craft S, Yaffe K, Weitlauf J, Vaughan L, Johnson KC, Padula CB et al..  2015.  Impact of Type 2 Diabetes and Postmenopausal Hormone Therapy on Incidence of Cognitive Impairment in Older Women.. Diabetes Care. 38(12):2316-24.
Brinton RD, Yao J, Yin F, Mack WJ, Cadenas E.  2015.  Perimenopause as a neurological transition state.. Nat Rev Endocrinol. 11(7):393-405.
Espeland MA, Brinton RDiaz, Manson JAE, Yaffe K, Hugenschmidt C, Vaughan L, Craft S, Edwards BJ, Casanova R, Masaki K et al..  2015.  Postmenopausal hormone therapy, type 2 diabetes mellitus, and brain volumes.. Neurology. 85(13):1131-8.
Frankowski KJ, Slauson SR, Lovell KM, Phillips AM, Streicher JM, Zhou L, Whipple DA, Schoenen FJ, Prisinzano TE, Bohn LM et al..  2015.  Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif.. Bioorg Med Chem. 23(14):3948-56.
Caldwell CC, Yao J, Brinton RDiaz.  2015.  Targeting the prodromal stage of Alzheimer's disease: bioenergetic and mitochondrial opportunities.. Neurotherapeutics. 12(1):66-80.
Ronaldson PT, Davis TP.  2015.  Targeting transporters: promoting blood-brain barrier repair in response to oxidative stress injury.. Brain Res. 1623:39-52.
Kumar S, Pan CC, Bloodworth JC, Nixon AB, Theuer C, Hoyt DG, Lee NY.  2014.  Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling.. Oncogene. 33(30):3970-9.
Zhang Y, Braithwaite A, Yuan Y, Streicher JM, Bilsky EJ.  2014.  Behavioral and cellular pharmacology characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan (NAQ) as a mu opioid receptor selective ligand.. Eur J Pharmacol. 736:124-30.
Thompson BJ, Ronaldson PT.  2014.  Drug delivery to the ischemic brain.. Adv Pharmacol. 71:165-202.
White AG, Watts GS, Lu Z, Meza-Montenegro MM, Lutz EA, Harber P, Burgess JL.  2014.  Environmental arsenic exposure and microbiota in induced sputum.. Int J Environ Res Public Health. 11(2):2299-313.
Rettberg JR, Yao J, Brinton RDiaz.  2014.  Estrogen: a master regulator of bioenergetic systems in the brain and body.. Front Neuroendocrinol. 35(1):8-30.
Sancheti H, Patil I, Kanamori K, Brinton RDiaz, Zhang W, Lin A-L, Cadenas E.  2014.  Hypermetabolic state in the 7-month-old triple transgenic mouse model of Alzheimer's disease and the effect of lipoic acid: a 13C-NMR study.. J Cereb Blood Flow Metab. 34(11):1749-60.
Garbe JC, Vrba L, Sputova K, Fuchs L, Novak P, Brothman AR, Jackson M, Chin K, LaBarge MA, Watts G et al..  2014.  Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations.. Cell Cycle. 13(21):3423-35.
Sancheti H, Kanamori K, Patil I, Brinton RDiaz, Ross BD, Cadenas E.  2014.  Reversal of metabolic deficits by lipoic acid in a triple transgenic mouse model of Alzheimer's disease: a 13C NMR study.. J Cereb Blood Flow Metab. 34(2):288-96.
Pan CC, Kumar S, Shah N, Hoyt DG, Hawinkels LJAC, Mythreye K, Lee NY.  2014.  Src-mediated post-translational regulation of endoglin stability and function is critical for angiogenesis.. J Biol Chem. 289(37):25486-96.
Fernandes SM, Lee YSun, Gillies RJ, Hruby VJ.  2014.  Synthesis and evaluation of bivalent ligands for binding to the human melanocortin-4 receptor.. Bioorg Med Chem. 22(22):6360-5.
Lozano-Ondoua AN, Symons-Liguori AM, Vanderah TW.  2013.  Cancer-induced bone pain: Mechanisms and models.. Neurosci Lett. 557 Pt A:52-9.
Zhou L, Lovell KM, Frankowski KJ, Slauson SR, Phillips AM, Streicher JM, Stahl E, Schmid CL, Hodder P, Madoux F et al..  2013.  Development of functionally selective, small molecule agonists at kappa opioid receptors.. J Biol Chem. 288(51):36703-16.
Ding F, Yao J, Rettberg JR, Chen S, Brinton RDiaz.  2013.  Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.. PLoS One. 8(11):e79977.
Zhao L, Mao Z, Chen S, Schneider LS, Brinton RD.  2013.  Early intervention with an estrogen receptor β-selective phytoestrogenic formulation prolongs survival, improves spatial recognition memory, and slows progression of amyloid pathology in a female mouse model of Alzheimer's disease.. J Alzheimers Dis. 37(2):403-19.
Petrov RR, Lee YSun, Vardanyan RS, Liu L, Ma S-W, Davis P, Lai J, Porreca F, Vanderah TW, Hruby VJ.  2013.  Effect of anchoring 4-anilidopiperidines to opioid peptides.. Bioorg Med Chem Lett. 23(11):3434-7.
Fuente-Martin E, Garcia-Caceres C, Morselli E, Clegg DJ, Chowen JA, Finan B, Brinton RD, Tschöp MH.  2013.  Estrogen, astrocytes and the neuroendocrine control of metabolism.. Rev Endocr Metab Disord. 14(4):331-8.
Brinton RD.  2013.  Neurosteroids as regenerative agents in the brain: therapeutic implications.. Nat Rev Endocrinol. 9(4):241-50.
Yao J, Zhao L, Mao Z, Chen S, Wong KCarmen, To J, Brinton RDiaz.  2013.  Potentiation of brain mitochondrial function by S-equol and R/S-equol estrogen receptor β-selective phytoSERM treatments.. Brain Res. 1514:128-41.