Year of Publication Titlesort descending Faculty Association
2015 (S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5. Rajesh Khanna, May Khanna, PhD
2016 (S)-Lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology. Rajesh Khanna, May Khanna, PhD, Amol Patwardhan, M.D., Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD, Yanhua Xie, Ph.D.
2017 16S rRNA gene sequencing on a benchtop sequencer: accuracy for identification of clinically important bacteria. George Watts, Ph.D.
2016 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-(4'-pyridylcarboxamido)morphinan (NAP) Modulating the Mu Opioid Receptor in a Biased Fashion. John M. Streicher, PhD
2012 17β-estradiol and progesterone regulate expression of β-amyloid clearance factors in primary neuron cultures and female rat brain. Roberta Diaz Brinton, Ph.D
2011 17β-Estradiol regulates insulin-degrading enzyme expression via an ERβ/PI3-K pathway in hippocampus: relevance to Alzheimer's prevention. Roberta Diaz Brinton, Ph.D
2011 2-Deoxy-D-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease. Roberta Diaz Brinton, Ph.D
2010 A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. Tally Largent-Milnes, PhD, Patrick W Mantyh, Todd Vanderah, PhD
2012 A dominant negative ERβ splice variant determines the effectiveness of early or late estrogen therapy after ovariectomy in rats. Roberta Diaz Brinton, Ph.D
2015 A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors. Rajesh Khanna, May Khanna, PhD, Tally Largent-Milnes, PhD, Todd Vanderah, PhD
2010 A novel mechanism of acid and bile acid-induced DNA damage involving Na+/H+ exchanger: implication for Barrett's oesophagus. George Watts, Ph.D.
2009 A select combination of clinically relevant phytoestrogens enhances estrogen receptor beta-binding selectivity and neuroprotective activities in vitro and in vivo. Roberta Diaz Brinton, Ph.D
2016 A single diamagnetic catalyCEST MRI contrast agent that detects cathepsin B enzyme activity by using a ratio of two CEST signals. Yeon Sun Lee
2017 A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function. Rajesh Khanna
2008 A structure-activity relationship study and combinatorial synthetic approach of C-terminal modified bifunctional peptides that are delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists. Tally Largent-Milnes, PhD, Edita Navratilova, Frank Porreca, PhD, Todd Vanderah, PhD
2013 Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism. Thomas P Davis, PhD, Patrick T Ronaldson, PhD, Todd Vanderah, PhD
2012 Activation of descending pain-facilitatory pathways from the rostral ventromedial medulla by cholecystokinin elicits release of prostaglandin-E₂ in the spinal cord. Josephine Lai , Ph.D., Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD
2016 Activation of Mitofusin2 by Smad2-RIN1 Complex during Mitochondrial Fusion. Nam Lee, Ph.D.
2012 Activation of TRPA1 on dural afferents: a potential mechanism of headache pain. Frank Porreca, PhD, Todd Vanderah, PhD
2016 Age, APOE and sex: Triad of risk of Alzheimer's disease. Roberta Diaz Brinton, Ph.D
2013 Age-dependent modulation of synaptic plasticity and insulin mimetic effect of lipoic acid on a mouse model of Alzheimer's disease. Roberta Diaz Brinton, Ph.D, Fei Yin, Ph.D.
2008 Agglomerative epigenetic aberrations are a common event in human breast cancer. George Watts, Ph.D.
2014 Allopregnanolone as regenerative therapeutic for Alzheimer's disease: translational development and clinical promise. Roberta Diaz Brinton, Ph.D
2012 Allopregnanolone increases the number of dopaminergic neurons in substantia nigra of a triple transgenic mouse model of Alzheimer's disease. Roberta Diaz Brinton, Ph.D
2015 Allopregnanolone preclinical acute pharmacokinetic and pharmacodynamic studies to predict tolerability and efficacy for Alzheimer's disease. Roberta Diaz Brinton, Ph.D