Publications

Year of Publicationsort descending Title Faculty Association
2011 2-Deoxy-D-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease. Roberta Diaz Brinton, Ph.D
2011 Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain. John M. Streicher, PhD
2011 Membrane estrogen receptors mediate calcium signaling and MAP kinase activation in individual hippocampal neurons. Roberta Diaz Brinton, Ph.D
2011 Discovery of a potent and efficacious peptide derivative for δ/μ opioid agonist/neurokinin 1 antagonist activity with a 2',6'-dimethyl-L-tyrosine: in vitro, in vivo, and NMR-based structural studies. Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD
2011 Inhibition of p38-MAPK signaling pathway attenuates breast cancer induced bone pain and disease progression in a murine model of cancer-induced bone pain. Frank Porreca, PhD, Todd Vanderah, PhD
2011 Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease. Roberta Diaz Brinton, Ph.D
2011 Hippocampal responsiveness to 17β-estradiol and equol after long-term ovariectomy: implication for a therapeutic window of opportunity. Roberta Diaz Brinton, Ph.D
2012 Activation of descending pain-facilitatory pathways from the rostral ventromedial medulla by cholecystokinin elicits release of prostaglandin-E₂ in the spinal cord. Josephine Lai , Ph.D., Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD
2012 Minireview: translational animal models of human menopause: challenges and emerging opportunities. Roberta Diaz Brinton, Ph.D
2012 Differential responses of progesterone receptor membrane component-1 (Pgrmc1) and the classical progesterone receptor (Pgr) to 17β-estradiol and progesterone in hippocampal subregions that support synaptic remodeling and neurogenesis. Roberta Diaz Brinton, Ph.D
2012 Repeated morphine treatment-mediated hyperalgesia, allodynia and spinal glial activation are blocked by co-administration of a selective cannabinoid receptor type-2 agonist. Tally Largent-Milnes, PhD, William R. Roeske, MD, Todd Vanderah, PhD, Eva Varga, Ph.D.
2012 Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice. Roberta Diaz Brinton, Ph.D
2012 Continuous versus cyclic progesterone exposure differentially regulates hippocampal gene expression and functional profiles. Roberta Diaz Brinton, Ph.D
2012 Structure-activity relationships of trimethoxybenzyl piperazine N-type calcium channel inhibitors. Frank Porreca, PhD, Todd Vanderah, PhD
2012 Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid. Roberta Diaz Brinton, Ph.D
2012 Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues. John M. Streicher, PhD
2012 A dominant negative ERβ splice variant determines the effectiveness of early or late estrogen therapy after ovariectomy in rats. Roberta Diaz Brinton, Ph.D
2012 Mechanisms of Bv8-induced biphasic hyperalgesia: increased excitatory transmitter release and expression. Michael H. Ossipov, Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD
2012 17β-estradiol and progesterone regulate expression of β-amyloid clearance factors in primary neuron cultures and female rat brain. Roberta Diaz Brinton, Ph.D
2012 Allopregnanolone increases the number of dopaminergic neurons in substantia nigra of a triple transgenic mouse model of Alzheimer's disease. Roberta Diaz Brinton, Ph.D
2012 The decreased expression of Beclin-1 correlates with progression to esophageal adenocarcinoma: the role of deoxycholic acid. George Watts, Ph.D.
2012 Intranasal delivery of biologics to the central nervous system. Jeffrey J. Lochhead, PhD
2012 Tachykinin NK₁ receptor antagonist co-administration attenuates opioid withdrawal-mediated spinal microglia and astrocyte activation. Victor Hruby, Ph.D., Tally Largent-Milnes, PhD, Todd Vanderah, PhD, Eva Varga, Ph.D.
2012 Estrogen regulation of mitochondrial bioenergetics: implications for prevention of Alzheimer's disease. Roberta Diaz Brinton, Ph.D
2012 Allopregnanolone reinstates tyrosine hydroxylase immunoreactive neurons and motor performance in an MPTP-lesioned mouse model of Parkinson's disease. Roberta Diaz Brinton, Ph.D

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