2015 |
Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states. |
Frank Porreca, PhD, Todd Vanderah, PhD |
2015 |
Orthopedic surgery and bone fracture pain are both significantly attenuated by sustained blockade of nerve growth factor. |
Patrick W Mantyh |
2015 |
Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. |
John M. Streicher, PhD |
2015 |
Design, synthesis, and biological evaluation of a series of bifunctional ligands of opioids/SSRIs. |
|
2015 |
Temperature differentially facilitates spontaneous but not evoked glutamate release from cranial visceral primary afferents. |
Tally Largent-Milnes, PhD |
2015 |
Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis. |
Todd Vanderah, PhD |
2015 |
Spinal dopaminergic projections control the transition to pathological pain plasticity via a D1/D5-mediated mechanism. |
Patrick W Mantyh |
2015 |
The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity. |
Roberta Diaz Brinton, Ph.D, Fei Yin, Ph.D. |
2015 |
The mixed-action delta/mu opioid agonist MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats, and induces in vitro markers of tolerance and dependence. |
John M. Streicher, PhD |
2015 |
Blockade of non-opioid excitatory effects of spinal dynorphin A at bradykinin receptors. |
Frank Porreca, PhD, Todd Vanderah, PhD |
2014 |
Neuropathic plasticity in the opioid and non-opioid actions of dynorphin A fragments and their interactions with bradykinin B2 receptors on neuronal activity in the rat spinal cord. |
Frank Porreca, PhD |
2014 |
Src-mediated post-translational regulation of endoglin stability and function is critical for angiogenesis. |
Nam Lee, Ph.D. |
2014 |
Three-dimensional printing surgical instruments: are we there yet? |
|
2014 |
Physiological temperatures drive glutamate release onto trigeminal superficial dorsal horn neurons. |
Tally Largent-Milnes, PhD |
2014 |
Differential neuroprotective potential of CRMP2 peptide aptamers conjugated to cationic, hydrophobic, and amphipathic cell penetrating peptides. |
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2014 |
Structure-activity relationships of non-opioid [des-Arg(7)]-dynorphin A analogues for bradykinin receptors. |
Frank Porreca, PhD |
2014 |
Capsaicin-responsive corneal afferents do not contain TRPV1 at their central terminals in trigeminal nucleus caudalis in rats. |
Tally Largent-Milnes, PhD |
2014 |
Discovery of amphipathic dynorphin A analogues to inhibit the neuroexcitatory effects of dynorphin A through bradykinin receptors in the spinal cord. |
Victor Hruby, Ph.D., Josephine Lai , Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD |
2014 |
Frontiers in therapeutic development of allopregnanolone for Alzheimer's disease and other neurological disorders. |
Roberta Diaz Brinton, Ph.D |
2014 |
Synthesis and evaluation of bivalent ligands for binding to the human melanocortin-4 receptor. |
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2014 |
External QX-314 inhibits evoked cranial primary afferent synaptic transmission independent of TRPV1. |
Tally Largent-Milnes, PhD |
2014 |
Animal models for opioid addiction drug discovery. |
Tally Largent-Milnes, PhD, Todd Vanderah, PhD |
2014 |
Behavioral and cellular pharmacology characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan (NAQ) as a mu opioid receptor selective ligand. |
John M. Streicher, PhD |
2014 |
Estrogen: a master regulator of bioenergetic systems in the brain and body. |
Roberta Diaz Brinton, Ph.D |
2014 |
Drug delivery to the ischemic brain. |
Patrick T Ronaldson, PhD, FAAPS |