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2015 |
The mixed-action delta/mu opioid agonist MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats, and induces in vitro markers of tolerance and dependence. |
John M. Streicher, PhD |
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2015 |
Blockade of non-opioid excitatory effects of spinal dynorphin A at bradykinin receptors. |
Frank Porreca, PhD, Todd Vanderah, PhD |
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2015 |
Impact of Type 2 Diabetes and Postmenopausal Hormone Therapy on Incidence of Cognitive Impairment in Older Women. |
Roberta Diaz Brinton, Ph.D |
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2015 |
Discovery of 5-substituted tetrahydronaphthalen-2yl-methyl with N-phenyl-N-(piperidin-4-yl)propionamide derivatives as potent opioid receptor ligands. |
Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD |
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2015 |
Therapeutic potential of peroxynitrite decomposition catalysts: a patent review. |
Todd Vanderah, PhD |
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2015 |
Targeting the prodromal stage of Alzheimer's disease: bioenergetic and mitochondrial opportunities. |
Roberta Diaz Brinton, Ph.D |
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2015 |
Epigenetic Regulation of GDF2 Suppresses Anoikis in Ovarian and Breast Epithelia. |
Nam Lee, Ph.D. |
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2015 |
White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease. |
Roberta Diaz Brinton, Ph.D, Fei Yin, Ph.D. |
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2015 |
Gemcitabine resistant pancreatic cancer cell lines acquire an invasive phenotype with collateral hypersensitivity to histone deacetylase inhibitors. |
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2015 |
Design and synthesis of novel bivalent ligands (MOR and DOR) by conjugation of enkephalin analogues with 4-anilidopiperidine derivatives. |
Victor Hruby, Ph.D., Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD |
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2014 |
Capsaicin-responsive corneal afferents do not contain TRPV1 at their central terminals in trigeminal nucleus caudalis in rats. |
Tally Largent-Milnes, PhD |
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2014 |
Discovery of amphipathic dynorphin A analogues to inhibit the neuroexcitatory effects of dynorphin A through bradykinin receptors in the spinal cord. |
Victor Hruby, Ph.D., Josephine Lai , Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD |
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2014 |
Estrogen: a master regulator of bioenergetic systems in the brain and body. |
Roberta Diaz Brinton, Ph.D |
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2014 |
Synthesis and evaluation of bivalent ligands for binding to the human melanocortin-4 receptor. |
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2014 |
External QX-314 inhibits evoked cranial primary afferent synaptic transmission independent of TRPV1. |
Tally Largent-Milnes, PhD |
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2014 |
Animal models for opioid addiction drug discovery. |
Tally Largent-Milnes, PhD, Todd Vanderah, PhD |
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2014 |
Reversal of metabolic deficits by lipoic acid in a triple transgenic mouse model of Alzheimer's disease: a 13C NMR study. |
Roberta Diaz Brinton, Ph.D |
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2014 |
Behavioral and cellular pharmacology characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan (NAQ) as a mu opioid receptor selective ligand. |
John M. Streicher, PhD |
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2014 |
Drug delivery to the ischemic brain. |
Patrick T Ronaldson, PhD, FAAPS |
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2014 |
Hypermetabolic state in the 7-month-old triple transgenic mouse model of Alzheimer's disease and the effect of lipoic acid: a 13C-NMR study. |
Roberta Diaz Brinton, Ph.D |
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2014 |
Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations. |
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2014 |
Differential regulation of collapsin response mediator protein 2 (CRMP2) phosphorylation by GSK3ß and CDK5 following traumatic brain injury. |
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2014 |
Intranasal drug delivery to the brain |
Jeffrey J. Lochhead, PhD |
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2014 |
Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling. |
Nam Lee, Ph.D. |
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2014 |
Hypoxia/reoxygenation stress signals an increase in organic anion transporting polypeptide 1a4 (Oatp1a4) at the blood-brain barrier: relevance to CNS drug delivery. |
Patrick T Ronaldson, PhD, FAAPS |
