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2015 |
The mixed-action delta/mu opioid agonist MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats, and induces in vitro markers of tolerance and dependence. |
John M. Streicher, PhD |
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2015 |
Blockade of non-opioid excitatory effects of spinal dynorphin A at bradykinin receptors. |
Frank Porreca, PhD, Todd Vanderah, PhD |
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2015 |
Discovery of 5-substituted tetrahydronaphthalen-2yl-methyl with N-phenyl-N-(piperidin-4-yl)propionamide derivatives as potent opioid receptor ligands. |
Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD |
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2015 |
Therapeutic potential of peroxynitrite decomposition catalysts: a patent review. |
Todd Vanderah, PhD |
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2015 |
The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity. |
Roberta Diaz Brinton, Ph.D, Fei Yin, Ph.D. |
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2015 |
Epigenetic Regulation of GDF2 Suppresses Anoikis in Ovarian and Breast Epithelia. |
Nam Lee, Ph.D. |
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2015 |
Gemcitabine resistant pancreatic cancer cell lines acquire an invasive phenotype with collateral hypersensitivity to histone deacetylase inhibitors. |
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2015 |
Design and synthesis of novel bivalent ligands (MOR and DOR) by conjugation of enkephalin analogues with 4-anilidopiperidine derivatives. |
Victor Hruby, Ph.D., Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD |
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2016 |
Cyclic non-opioid dynorphin A analogues for the bradykinin receptors. |
Frank Porreca, PhD |
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2016 |
Structure-Activity Relationships of [des-Arg(7)]Dynorphin A Analogues at the κ Opioid Receptor. |
Victor Hruby, Ph.D., Tally Largent-Milnes, PhD, Frank Porreca, PhD, John M. Streicher, PhD, Todd Vanderah, PhD |
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2016 |
Altered brain energetics induces mitochondrial fission arrest in Alzheimer's Disease. |
Roberta Diaz Brinton, Ph.D |
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2016 |
(S)-Lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology. |
Frank Porreca, PhD, Todd Vanderah, PhD |
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2016 |
Cyclic Opioid Peptides. |
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2016 |
Identifying postmenopausal women at risk for cognitive decline within a healthy cohort using a panel of clinical metabolic indicators: potential for detecting an at-Alzheimer's risk metabolic phenotype. |
Roberta Diaz Brinton, Ph.D |
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2016 |
Biphalin: The Foundation of Bivalent Ligands. |
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2016 |
Sensitization of Ion Channels Contributes to Central and Peripheral Dysfunction in Neurofibromatosis Type 1. |
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2016 |
Regulation of gene expression and mitochondrial dynamics by SMAD. |
Nam Lee, Ph.D. |
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2016 |
Enkephalin analogues with N-phenyl-N-(piperidin-2-ylmethyl)propionamide derivatives: Synthesis and biological evaluations. |
Victor Hruby, Ph.D., Tally Largent-Milnes, PhD, Frank Porreca, PhD, Todd Vanderah, PhD |
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2016 |
Highlights From the AM Assoc of Pharmaceutical Scientists/International Transporter Consortium Joint Workshop on Drug Transporters in Absorption, Distribution, Metabolism, and Excretion: From the Bench to the Bedside - Clinical Pharmacology Considerations |
Patrick T Ronaldson, PhD, FAAPS |
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2016 |
Sex differences in metabolic aging of the brain: insights into female susceptibility to Alzheimer's disease. |
Roberta Diaz Brinton, Ph.D |
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2016 |
Various modifications of the amphipathic dynorphin A pharmacophore for rat brain bradykinin receptors. |
Frank Porreca, PhD |
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2016 |
The cystine/glutamate antiporter system xc- drives breast tumor cell glutamate release and cancer-induced bone pain. |
Tally Largent-Milnes, PhD, Patrick W Mantyh, Todd Vanderah, PhD |
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2016 |
Neuroendocrinology: Oestrogen therapy affects brain structure but not function. |
Roberta Diaz Brinton, Ph.D |
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2016 |
Enkephalin-Fentanyl Multifunctional Opioids as Potential Neuroprotectants for Ischemic Stroke Treatment. |
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2016 |
Brain and White Matter Hyperintensity Volumes After 10 Years of Random Assignment to Lifestyle Intervention. |
Roberta Diaz Brinton, Ph.D |
