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2013 |
Maintenance of mitochondrial genomic integrity in the absence of manganese superoxide dismutase in mouse liver hepatocytes. |
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2013 |
Ovariectomy induces a shift in fuel availability and metabolism in the hippocampus of the female transgenic model of familial Alzheimer's. |
Roberta Diaz Brinton, Ph.D |
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2013 |
Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention. |
Roberta Diaz Brinton, Ph.D |
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2013 |
Early intervention with an estrogen receptor β-selective phytoestrogenic formulation prolongs survival, improves spatial recognition memory, and slows progression of amyloid pathology in a female mouse model of Alzheimer's disease. |
Roberta Diaz Brinton, Ph.D |
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2012 |
17β-estradiol and progesterone regulate expression of β-amyloid clearance factors in primary neuron cultures and female rat brain. |
Roberta Diaz Brinton, Ph.D |
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2012 |
Intranasal delivery of biologics to the central nervous system. |
Jeffrey J. Lochhead, PhD |
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2012 |
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy. |
John M. Streicher, PhD |
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2012 |
Repeated morphine treatment-mediated hyperalgesia, allodynia and spinal glial activation are blocked by co-administration of a selective cannabinoid receptor type-2 agonist. |
Tally Largent-Milnes, PhD, Todd Vanderah, PhD, Eva Varga, Ph.D. |
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2012 |
Tachykinin NK₁ receptor antagonist co-administration attenuates opioid withdrawal-mediated spinal microglia and astrocyte activation. |
Victor Hruby, Ph.D., Tally Largent-Milnes, PhD, Todd Vanderah, PhD, Eva Varga, Ph.D. |
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2012 |
Structure-activity relationships of trimethoxybenzyl piperazine N-type calcium channel inhibitors. |
Frank Porreca, PhD, Todd Vanderah, PhD |
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2012 |
Mechanisms of Bv8-induced biphasic hyperalgesia: increased excitatory transmitter release and expression. |
Michael H. Ossipov, Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD |
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2012 |
Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues. |
John M. Streicher, PhD |
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2012 |
Selective oestrogen receptor modulators differentially potentiate brain mitochondrial function. |
Roberta Diaz Brinton, Ph.D |
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2012 |
Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain. |
Thomas P Davis, PhD, Jeffrey J. Lochhead, PhD, Patrick T Ronaldson, PhD, FAAPS |
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2012 |
Differential responses of progesterone receptor membrane component-1 (Pgrmc1) and the classical progesterone receptor (Pgr) to 17β-estradiol and progesterone in hippocampal subregions that support synaptic remodeling and neurogenesis. |
Roberta Diaz Brinton, Ph.D |
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2012 |
The matrix protein CCN1/CYR61 is required for α(V)β5-mediated cancer cell migration. |
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2012 |
Minireview: translational animal models of human menopause: challenges and emerging opportunities. |
Roberta Diaz Brinton, Ph.D |
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2012 |
Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid. |
Roberta Diaz Brinton, Ph.D |
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2012 |
The decreased expression of Beclin-1 correlates with progression to esophageal adenocarcinoma: the role of deoxycholic acid. |
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2012 |
A dominant negative ERβ splice variant determines the effectiveness of early or late estrogen therapy after ovariectomy in rats. |
Roberta Diaz Brinton, Ph.D |
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2012 |
Estrogen regulation of mitochondrial bioenergetics: implications for prevention of Alzheimer's disease. |
Roberta Diaz Brinton, Ph.D |
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2011 |
Synthesis and biological evaluation of new opioid agonist and neurokinin-1 antagonist bivalent ligands. |
Peg Davis, Victor Hruby, Ph.D., Josephine Lai , Ph.D., Frank Porreca, PhD, Todd Vanderah, PhD, Eva Varga, Ph.D. |
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2011 |
Estrogen receptor β-selective phytoestrogenic formulation prevents physical and neurological changes in a preclinical model of human menopause. |
Roberta Diaz Brinton, Ph.D |
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2011 |
17β-Estradiol regulates insulin-degrading enzyme expression via an ERβ/PI3-K pathway in hippocampus: relevance to Alzheimer's prevention. |
Roberta Diaz Brinton, Ph.D |
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2011 |
Estrogen protection against mitochondrial toxin-induced cell death in hippocampal neurons: antagonism by progesterone. |
Roberta Diaz Brinton, Ph.D |
